Evidence map›Paper›PMID 26989787›Full record

ArticleNanoImpact2016

Effects of intratracheally instilled laser printer-emitted engineered nanoparticles in a mouse model: A case study of toxicological implications from nanomaterials released during consumer use.

Sandra V Pirela, Xiaoyan Lu, Isabelle Miousse, Jennifer D Sisler, Yong Qian, Nancy Guo, Igor Koturbash, Vincent Castranova, Treye Thomas, John Godleski and 1 more

Open access · greenAbstract read
In one paragraph

Article in NanoImpact, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
6.8field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 48 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 1 country.

Sandra V PirelaDepartment of Environmental Health, Center for Nanotechnology and Nanotoxicology, T. H. Chan School of Public Health, Harvard University, Boston, MA, United States.
Xiaoyan LuDepartment of Environmental Health, Center for Nanotechnology and Nanotoxicology, T. H. Chan School of Public Health, Harvard University, Boston, MA, United States.
Isabelle MiousseDepartment of Environmental and Occupational Health, College of Public Health, University of Arkansas for Medical Sciences, Little Rock, AR, United States.
Jennifer D SislerPathology and Physiology Research Branch, Health Effects Laboratory Division, National Institute for Occupational Safety and Health, Morgantown, WV, United States.
Yong QianPathology and Physiology Research Branch, Health Effects Laboratory Division, National Institute for Occupational Safety and Health, Morgantown, WV, United States.
Nancy GuoDepartment of Pharmaceutical Sciences/Mary Babb Randolph Cancer Center, West Virginia University, Morgantown, WV, United States.
Igor KoturbashDepartment of Environmental and Occupational Health, College of Public Health, University of Arkansas for Medical Sciences, Little Rock, AR, United States.
Vincent CastranovaDepartment of Pharmaceutical Sciences/Mary Babb Randolph Cancer Center, West Virginia University, Morgantown, WV, United States.
Treye ThomasU.S. Consumer Product Safety Commission, Office of Hazard Identification and Reduction, Rockville, MD, United States.
John GodleskiDepartment of Environmental Health, Center for Nanotechnology and Nanotoxicology, T. H. Chan School of Public Health, Harvard University, Boston, MA, United States.
Philip DemokritouDepartment of Environmental Health, Center for Nanotechnology and Nanotoxicology, T. H. Chan School of Public Health, Harvard University, Boston, MA, United States.
Harvard University · USNational Institute for Occupational Safety and Health · USUniversity of Arkansas for Medical Sciences · USWest Virginia University · USUnited States Consumer Product Safety Commission · US

Funding

The Role o f Tetrahydrobiopterin (BH4) Bioavailability in Radiation-induced Skin InjuryP20GM109005 · NIGMS · UNIV OF ARKANSAS FOR MED SCIS · PI PARKER, PEARMAN · 2015 to 2024
$21.1M
Training Program in Molecular and Integrative Physiological SciencesT32HL007118 · NHLBI · HARVARD UNIVERSITY (SCH OF PUBLIC HLTH) · PI LU, QUAN · 1985 to 2025
$14.3M
Arkansas Center for Clinical and Translational ResearchUL1TR000039 · NCATS · UNIV OF ARKANSAS FOR MED SCIS · PI BECK, CORNELIA MARIE, JAMES, LAURA P · 2012 to 2014
$10.0M
Systematic assessment of multi-walled carbon nanotubes in pulmonary diseaseR01ES021764 · NIEHS · WEST VIRGINIA UNIVERSITY · PI GUO, NANCY LAN · 2012 to 2016
$1.7M
Arkansas Center for Clinical Translational ResearchKL2TR000063 · NCATS · UNIV OF ARKANSAS FOR MED SCIS · PI BECK, CORNELIA MARIE, JAMES, LAURA P · 2012 to 2014
$459k
Intramural CDC HHS CC999999NCATS NIH HHS KL2 TR000063NCATS NIH HHS UL1 TR000039NHLBI NIH HHS T32 HL007118NIEHS NIH HHS R01 ES021764NIGMS NIH HHS P20 GM109005
6 · The paper itself

Abstract

Incorporation of engineered nanomaterials (ENMs) into toners used in laser printers has led to countless quality and performance improvements. However, the release of ENMs during printing (consumer use) has raised concerns about their potential adverse health effects. The aim of this study was to use "real world" printer-emitted particles (PEPs), rather than raw toner powder, and assess the pulmonary responses following exposure by intratracheal instillation. Nine-week old male

Indexed as

EpigeneticsInflammationLaser printersNanoparticles

Identifiers

PMID26989787
PMCPMC4791579
OpenAlexW2274007157

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.