Evidence map›Paper›PMID 26989729›Full record

ArticleReports of biochemistry & molecular biology2014

Recurrent pregnancy loss in a subject with heterozygote factor V Leiden mutation; a case report.

Reza Ebrahimzadeh-Vesal, Roza Azam, Arvin Ghazarian, Mogge Hajesmaeili, Najmeh Ranji, Mohammad Reza Ezzati, Mehrdad Sadri, Mohammad Ali Mohammadi, Siamak Khavandi

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PubMed Full text at PMC
In one paragraph

Article in Reports of biochemistry & molecular biology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 83% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Reza Ebrahimzadeh-VesalDepartment of Medical Genetics, Faculty of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
Roza AzamDepartment of Medical Genetics, Faculty of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
Arvin GhazarianDepartment of Medical Genetics, Faculty of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
Mogge HajesmaeiliDepartment of Biology, Islamic Azad University of Parand, Tehran, Iran.
Najmeh RanjiDepartment of Genetics, Faculty of Sciences, Islamic Azad University, Rasht Branch, Rasht, Iran.
Mohammad Reza EzzatiFaculty of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
Mehrdad SadriFaculty of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
Mohammad Ali MohammadiFaculty of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
Siamak KhavandiFaculty of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
Tehran University of Medical Sciences · IRIslamic Azad University Rasht Branch · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recurrent pregnancy loss is usually defined as the loss of two or more consecutive pregnancies before 20 weeks of gestation, which occurs in approximately 5% of reproductive-aged women. It has been suggested that women with thrombophilia have an increased risk of pregnancy loss and other adverse pregnancy outcomes. Thrombophilia is an important predisposition to blood clot formation and is considered as a significant risk factor for recurrent pregnancy loss. The inherited predisposition to thrombophilia is most often associated with factor V Leiden mutation, prothrombin G20210A mutation, and methylenetetrahydrofolate reductase C677T and A1298C gene variants. The net effect is an increased cleavage of prothrombin to thrombin and excessive blood coagulation.

Indexed as

Factor V Leiden mutationHereditary thrombophiliaRecurrent pregnancy loss

Identifiers

PMID26989729
PMCPMC4757054
OpenAlexW2299013614

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.