ArticleRSC advances2016
Influence of silk-silica fusion protein design on silica condensation
Article in RSC advances, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
12 citing papers in PubMed.
- Genetic Functionalization of Protein-Based Biomaterials via Protein Fusions.Biomacromolecules · 2024Review
- Recombinant fibrous protein biomaterials meet skin tissue engineering.Frontiers in bioengineering and biotechnology · 2024Review
- Factors Influencing Properties of Spider Silk Coatings and Their Interactions within a Biological Environment.Journal of functional biomaterials · 2023Review
- Effect of the silica nanoparticle size on the osteoinduction of biomineralized silk-silica nanocomposites.Acta biomaterialia · 2021Article
- Spider Silk for Tissue Engineering Applications.Molecules (Basel, Switzerland) · 2020Review
- Design, Fabrication, and Function of Silk-Based Nanomaterials.Advanced functional materials · 2018Article
- Ionic Liquid-Assisted Synthesis of Mesoporous Silk Fibroin/Silica Hybrids for Biomedical Applications.ACS omega · 2018Article
- [Silicification of silk fibroin and their application in bone tissue engineering].Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi · 2018Review
- Intracellular Pathways Involved in Bone Regeneration Triggered by Recombinant Silk-silica Chimeras.Advanced functional materials · 2018Article
- Multiscale design and synthesis of biomimetic gradient protein/biosilica composites for interfacial tissue engineering.Biomaterials · 2017Article
- Synergistic Integration of Experimental and Simulation Approaches for the de Novo Design of Silk-Based Materials.Accounts of chemical research · 2017Review
- Osteoinductive recombinant silk fusion proteins for bone regeneration.Acta biomaterialia · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
Biomaterial design via genetic engineering can be utilized for the rational functionalization of proteins to promote biomaterial integration and tissue regeneration. Spider silk has been extensively studied for its biocompatibility, biodegradability and extraordinary material properties. As a protein-based biomaterial, recombinant DNA derived derivatives of spider silks have been modified with biomineralization domains which lead to silica deposition and potentially accelerated bone regeneration. However, the influence of the location of the R5 (SSKKSGSYSGSKGSKRRIL) silicifying domain fused with the spider silk protein sequence on the biosilicification process remains to be determined. Here we designed two silk-R5 fusion proteins that differed in the location of the R5 peptide, C-
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.