Evidence map›Paper›PMID 26989295›Full record

ArticleMRS bulletin2015

Biopolymers and supramolecular polymers as biomaterials for biomedical applications.

Ronit Freeman, Job Boekhoven, Matthew B Dickerson, Rajesh R Naik, Samuel I Stupp

Abstract read
In one paragraph

Article in MRS bulletin, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Article
  2. Article
  3. A bioactive supramolecular and covalent polymer scaffold for cartilage repair in a sheep model.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  4. Article
  5. Review
  6. Article
  7. Review
  8. Article
  9. Review
  10. Review
  11. Review
  12. Review
  13. Self-Assembling Peptides: From Design to Biomedical Applications.International journal of molecular sciences · 2021
    Review
  14. Article
  15. Article
  16. Review
  17. Peptide hormones and lipopeptides: from self-assembly to therapeutic applications.Journal of peptide science : an official publication of the European Peptide Society · 2017
    Review
  18. Review
  19. Cardiovascular Regenerative Technologies: Update and Future Outlook.Transfusion medicine and hemotherapy : offizielles Organ der Deutschen Gesellschaft fur Transfusionsmedizin und Immunhamatologie · 2016
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ronit FreemanSimpson Querrey Institute of BioNanotechnology, Northwestern University, Chicago, IL 60611, USA.
Job BoekhovenSimpson Querrey Institute of BioNanotechnology, Northwestern University, Chicago, IL 60611, USA.
Matthew B DickersonMaterials and Manufacturing Directorate, Air Force Research Laboratory, Wright-Patterson Air Force Base, Ohio 45433-7702.
Rajesh R Naik711 Human Performance Wing, Air Force Research Laboratory, Wright-Patterson Air Force Base, Ohio 45433-7702.
Samuel I StuppSimpson Querrey Institute of BioNanotechnology, Northwestern University, Chicago, IL 60611, USA; Departments of Materials and Science & Engineering, Chemistry, Medicine, and Biomedical Engineering, Northwestern University, Evanston, IL 60208, USA.

Funding

Small Animal Surgery and HistologyP01HL108795 · NHLBI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI LOSORDO, DOUGLAS W · 2011 to 2015
$10.7M
Regenerative Scaffold Technologies for CNS and DiabetesR01EB003806 · NIBIB · NORTHWESTERN UNIVERSITY AT CHICAGO · PI STUPP, SAMUEL I · 2004 to 2015
$10.7M
Nanotechnology Strategies for Growth of Bones and TeethR01DE015920 · NIDCR · NORTHWESTERN UNIVERSITY AT CHICAGO · PI SNEAD, MALCOLM L., STUPP, SAMUEL I · 2005 to 2015
$5.8M
Novel Vehicles for Targeted Cardiovascular RepairR01HL116577 · NHLBI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI KIBBE, MELINA RAE, STUPP, SAMUEL I · 2013 to 2016
$4.3M
NHLBI NIH HHS P01 HL108795NHLBI NIH HHS R01 HL116577NIBIB NIH HHS R01 EB003806NIDCR NIH HHS R01 DE015920
6 · The paper itself

Abstract

Protein- and peptide-based structural biopolymers are abundant building blocks of biological systems. Either in their natural forms, such as collagen, silk or fibronectin, or as related synthetic materials they can be used in various technologies. An emerging area is that of biomimetic materials inspired by protein-based biopolymers, which are made up of small molecules rather than macromolecules and can therefore be described as supramolecular polymers. These materials are very useful in biomedical applications because of their ability to imitate the extracellular matrix both in architecture and their capacity to signal cells. This article describes important features of the natural extracellular matrix and highlight how these features are being incorporated into biomaterials composed of biopolymers and supramolecular polymers. We particularly focus on the structures, properties, and functions of collagen, fibronectin, silk, and the supramolecular polymers inspired by them as biomaterials for regenerative medicine.

Indexed as

biomedicalbiomimetic (assembly)nanostructureself-assembly

Identifiers

PMID26989295
PMCPMC4790466

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.