ArticleDevelopment (Cambridge, England)2016
Differential regulation of meristem size, morphology and organization by the ERECTA, CLAVATA and class III HD-ZIP pathways.
Article in Development (Cambridge, England), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
29 citing papers in PubMed, 62 citations in OpenAlex.
- Shoot apical meristem morphoanatomy of the Mexican cactus Mammillaria san-angelensis and its significance for evolutionary developmental biology.Annals of botany · 2026Article
- Altered Meristem Initiation Is Associated with IncreasedBiology · 2026Article
- ERECTA genes and their ligands regulate shoot and inflorescence architecture in maize.Nature communications · 2026Article
- Membrane transport of root-borne trans-zeatin riboside maintains the cytokinin homeostasis in shoots.Journal of experimental botany · 2025Article
- Behind phyllotaxis, within the meristem: a REM-ARF complex shapes inflorescence in Arabidopsis thaliana.The Plant journal : for cell and molecular biology · 2025Article
- Systematic expression analysis of cysteine-rich secretory proteins, antigen 5, and pathogenesis-related 1 protein (CAP) superfamily inPlant direct · 2024Article
- CLAVATA3 Signaling Buffers Arabidopsis Shoot Apical Meristem Activity in Response to Photoperiod.International journal of molecular sciences · 2024Article
- Coordination of shoot apical meristem shape and identity by APETALA2 during floral transition in Arabidopsis.Nature communications · 2024Article
- The Ins and Outs of Homeodomain-Leucine Zipper/Hormone Networks in the Regulation of Plant Development.International journal of molecular sciences · 2024Review
- Cytokinin signaling regulates two-stage inflorescence arrest in Arabidopsis.Plant physiology · 2023Article
- Initiation of aboveground organ primordia depends on combined action of auxin, ERECTA family genes, and PINOID.Plant physiology · 2022Article
- microRNA 166: an evolutionarily conserved stress biomarker in land plants targeting HD-ZIP family.Physiology and molecular biology of plants : an international journal of functional plant biology · 2021Review
- Phyllotaxis: from classical knowledge to molecular genetics.Journal of plant research · 2021Review
- Paf1c defects challenge the robustness of flower meristem termination inDevelopment (Cambridge, England) · 2019Article
- Article
- Evolution of buffering in a genetic circuit controlling plant stem cell proliferation.Nature genetics · 2019Article
- Stem cells within the shoot apical meristem: identity, arrangement and communication.Cellular and molecular life sciences : CMLS · 2019Review
- Domain-specific expression of meristematic genes is defined by the LITTLE ZIPPER protein DTM in tomato.Communications biology · 2019Article
- Comparison Between Flat and Round Peaches, Genomic Evidences of Heterozygosity Events.Frontiers in plant science · 2019Article
- EPFL Signals in the Boundary Region of the SAM Restrict Its Size and Promote Leaf Initiation.Plant physiology · 2019Article
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The shoot apical meristem (SAM) of angiosperm plants is a small, highly organized structure that gives rise to all above-ground organs. The SAM is divided into three functional domains: the central zone (CZ) at the SAM tip harbors the self-renewing pluripotent stem cells and the organizing center, providing daughter cells that are continuously displaced into the interior rib zone (RZ) or the surrounding peripheral zone (PZ), from which organ primordia are initiated. Despite the constant flow of cells from the CZ into the RZ or PZ, and cell recruitment for primordium formation, a stable balance is maintained between the distinct cell populations in the SAM. Here we combined an in-depth phenotypic analysis with a comparative RNA-Seq approach to characterize meristems from selected combinations of clavata3 (clv3), jabba-1D (jba-1D) and erecta (er) mutants of Arabidopsis thaliana We demonstrate that CLV3 restricts meristem expansion along the apical-basal axis, whereas class III HD-ZIP and ER pathways restrict meristem expansion laterally, but in distinct and possibly perpendicular orientations. Our k-means analysis reveals that clv3, jba-1D/+ and er lead to meristem enlargement by affecting different aspects of meristem function; for example, clv3 displays an increase in the stem cell population, whereas jba-1D/+ er exhibits an increase in mitotic activity and in the meristematic cell population. Our analyses demonstrate that a combined genetic and mRNA-Seq comparative approach provides a precise and sensitive method to identify cell type-specific transcriptomes in a small structure, such as the SAM.
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