ArticleDatabase : the journal of biological databases and curation2016
An integrative data analysis platform for gene set analysis and knowledge discovery in a data warehouse framework.
Article in Database : the journal of biological databases and curation, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
18 citing papers in PubMed.
- Subset binding enables detection of multimodal patient subgroup patterns and drug target discovery in idiopathic pulmonary fibrosis.Briefings in bioinformatics · 2026Article
- DOF gene family in P. sativum (L.): comprehensive genomic identification, phylogenetic examination, evolutionary growth, and expression analysis.BMC genomics · 2025Article
- TargetMine 2022: a new vision into drug target analysis.Bioinformatics (Oxford, England) · 2022Article
- Article
- Key regulatory genes and signaling pathways involved in islet culture: a bioinformatic analysis.International journal of clinical and experimental pathology · 2021Article
- MANTA, an integrative database and analysis platform that relates microbiome and phenotypic data.PloS one · 2020Article
- Integrative Analysis Reveals Common and Unique Roles of Tetraspanins in Fibrosis and Emphysema.Frontiers in genetics · 2020Article
- Sexual dimorphism in brain transcriptomes of Amami spiny rats (Tokudaia osimensis): a rodent species where males lack the Y chromosome.BMC genomics · 2019Article
- 'One DB to rule them all'-the RING: a Regulatory INteraction Graph combining TFs, genes/proteins, SNPs, diseases and drugs.Database : the journal of biological databases and curation · 2019Article
- Assessing drug target suitability using TargetMine.F1000Research · 2019Article
- The TargetMine Data Warehouse: Enhancement and Updates.Frontiers in genetics · 2019Article
- Search for Therapeutic Agents for Cardiac Arrest Using a Drug Discovery Tool and Large-Scale Medical Information Database.Frontiers in pharmacology · 2019Article
- GenCoNet - A Graph Database for the Analysis of Comorbidities by Gene Networks.Journal of integrative bioinformatics · 2018Article
- Double deletion of tetraspanins CD9 and CD81 in mice leads to a syndrome resembling accelerated aging.Scientific reports · 2018Article
- Integrating sequence and gene expression information predicts genome-wide DNA-binding proteins and suggests a cooperative mechanism.Nucleic acids research · 2018Article
- Interactive Toxicogenomics: Gene set discovery, clustering and analysis in Toxygates.Scientific reports · 2017Article
- Hypothalamic transcriptomic alterations in male and female California mice (Physiological reports · 2017Article
- Inflammation Thread Runs across Medical Laboratory Specialities.Mediators of inflammation · 2016Review
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Data analysis is one of the most critical and challenging steps in drug discovery and disease biology. A user-friendly resource to visualize and analyse high-throughput data provides a powerful medium for both experimental and computational biologists to understand vastly different biological data types and obtain a concise, simplified and meaningful output for better knowledge discovery. We have previously developed TargetMine, an integrated data warehouse optimized for target prioritization. Here we describe how upgraded and newly modelled data types in TargetMine can now survey the wider biological and chemical data space, relevant to drug discovery and development. To enhance the scope of TargetMine from target prioritization to broad-based knowledge discovery, we have also developed a new auxiliary toolkit to assist with data analysis and visualization in TargetMine. This toolkit features interactive data analysis tools to query and analyse the biological data compiled within the TargetMine data warehouse. The enhanced system enables users to discover new hypotheses interactively by performing complicated searches with no programming and obtaining the results in an easy to comprehend output format. Database URL: http://targetmine.mizuguchilab.org.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.