Evidence map›Paper›PMID 26988929›Full record

SynthesisStatistical methods in medical research2018

Bayesian bivariate meta-analysis of correlated effects: Impact of the prior distributions on the between-study correlation, borrowing of strength, and joint inferences.

Danielle L Burke, Sylwia Bujkiewicz, Richard D Riley

Abstract readMeta-Analysis
In one paragraph

Synthesis in Statistical methods in medical research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Article
  5. Article
  6. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Danielle L Burke1 Research Institute for Primary Care and Health Sciences, Keele University, Staffordshire, UK.
Sylwia Bujkiewicz2 Biostatistics Group, Department of Health Sciences, University of Leicester, Leicester, UK.
Richard D Riley1 Research Institute for Primary Care and Health Sciences, Keele University, Staffordshire, UK.

Funding

Medical Research Council G0800808Medical Research Council MR/J013595/1Medical Research Council MR/J013595/2Medical Research Council MR/L009854/1
6 · The paper itself

Abstract

Multivariate random-effects meta-analysis allows the joint synthesis of correlated results from multiple studies, for example, for multiple outcomes or multiple treatment groups. In a Bayesian univariate meta-analysis of one endpoint, the importance of specifying a sensible prior distribution for the between-study variance is well understood. However, in multivariate meta-analysis, there is little guidance about the choice of prior distributions for the variances or, crucially, the between-study correlation, ρ

Indexed as

Bayes TheoremMultivariate AnalysisBiostatisticsComputer SimulationData Interpretation, StatisticalHumansModels, StatisticalTreatment OutcomeBayesbivariate/multivariate meta-analysiscorrelationmultiple outcomesprior distributionssimulation study

Identifiers

PMID26988929
PMCPMC5810917

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.