SynthesisScientific reports2016
ABO blood group system and the coronary artery disease: an updated systematic review and meta-analysis.
Synthesis in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06149923 (Association Between ABO Polymorphism and Gastric/Colorectal Cancers), which is not on this map. Cited by 63 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Association Between ABO Polymorphism and Gastric/Colorectal Cancers
Who cites it
63 citing papers in PubMed, 4 syntheses or guidelines pooled it, 136 citations in OpenAlex.
- ABO and Rhesus blood groups and multiple health outcomes: an umbrella review of systematic reviews with meta-analyses of observational studies.BMC medicine · 2024Pooled it
- Pooled it
- Genome-wide meta-analysis of phytosterols reveals five novel loci and a detrimental effect on coronary atherosclerosis.Nature communications · 2022Pooled it
- Pooled it
- A Prospective, Randomized Trial Comparing Hydromorphone and Nalbuphine for Postcesarean Patient-Controlled Analgesia and Developing a Risk Prediction Model for Inadequate Analgesia.Drug design, development and therapy · 2025Trial
- A narrative review of the epidemiological and mechanistic associations between ABO blood groups and diseases: focusing on cardiovascular diseases, cancers, diabetes, malaria, COVID-19 and rheumatic diseases.Annals of medicine · 2026Review
- Relationship of ABO blood groups with metabolic syndrome and its metabolic abnormalities in a population in North Lahore.Pakistan journal of medical sciences · 2026Article
- ABO Blood Types and Mortality in Patients Undergoing Hemodialysis.Kidney international reports · 2026Article
- Association of ABO blood group and coronary heart disease in blood donors-Results from a cohort study in Australia.Transfusion · 2026Article
- Article
- Add-Ons of Heart Disease from the Cardiosurgical Perspective: Gender, Blood Groups and Renal Function.Medical sciences (Basel, Switzerland) · 2026Article
- ABO Blood Groups, Lipids, and Coronary CT Imaging in A Japanese Single-Center Cohort.Medical sciences (Basel, Switzerland) · 2026Article
- Blood Types May Be Involved in the Occurrence of Coronary Heart Disease Through Serum Lipids.BioMed research international · 2026Article
- Are Blood Groups a Predictive Factor in Determining the Severity of Coronary Artery Disease in Patients Undergoing Coronary Heart Surgery?Brazilian journal of cardiovascular surgery · 2026Article
- B blood type indicates poorer overall survival in patients with severe burn injuries: a case-control study.Annals of medicine · 2025Article
- ABO Blood Type Associations with Physical, Mental, and Biochemical Characteristics in a Taiwanese Population.Life (Basel, Switzerland) · 2025Article
- Integrative genetic analysis of shared genetic architecture of stroke and coronary artery disease: implications for pharmacist-led precision medicine.International journal of clinical pharmacy · 2025Article
- ABO exon polymorphisms are related to ischemic stroke in a Chinese Han population.BMC medical genomics · 2025Article
- ABO/rhesus D blood systems and health indices: a preliminary study to find an association among healthy dwellers of Anuradhapura, Sri Lanka.BMC research notes · 2025Article
- ABO Blood Type and Short-Term Mortality in Patients With Infection-Associated Disseminated Intravascular Coagulation.European journal of haematology · 2025Article
3 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
ABO blood group system, a well-known genetic risk factor, has clinically been demonstrated to be linked with thrombotic vascular diseases. However, the relationship between ABO blood group and coronary artery disease (CAD) is still controversial. We here performed an updated meta-analysis of the related studies and tried to elucidate the potential role of ABO blood group as a risk factor for CAD. All detectable case-control and cohort studies comparing the risk of CAD in different ABO blood groups were collected for this analysis through searching PubMed, Embase, and the Cochrane Library. Ultimately, 17 studies covering 225,810 participants were included. The combined results showed that the risk of CAD was significantly higher in blood group A (OR = 1.14, 95% CI = 1.03 to 1.26, p = 0.01) and lower in blood group O (OR = 0.85, 95% CI = 0.78 to 0.94, p = 0.0008). Even when studies merely about myocardial infarction (MI) were removed, the risk of CAD was still significantly higher in blood group A (OR = 1.05, 95% CI = 1.00 to 1.10, p = 0.03) and lower in blood group O (OR = 0.89, 95% CI = 0.85 to 0.93, p < 0.00001). This updated systematic review and meta-analysis indicated that both blood group A and non-O were the risk factors of CAD.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.