Evidence map›Paper›PMID 26988423›Full record

ArticleJournal of substance abuse treatment2016

Hepatitis C Virus Testing and Treatment Among Persons Receiving Buprenorphine in an Office-Based Program for Opioid Use Disorders.

Katelyn J Carey, Wei Huang, Benjamin P Linas, Judith I Tsui

Open access · greenAbstract read
In one paragraph

Article in Journal of substance abuse treatment, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
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  7. Article
  8. Review
  9. Opioid epidemic and liver disease.JHEP reports : innovation in hepatology · 2019
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Katelyn J CareyBoston University School of Medicine, 810 Massachusetts Avenue, Boston, MA 02118, USA. Electronic address: kjcarey@bu.edu.
Wei HuangBoston University School of Public Health, 715 Albany Street, Talbot Building, Boston, MA 02118, USA. Electronic address: weih@bu.edu.
Benjamin P LinasBoston University School of Medicine, 810 Massachusetts Avenue, Boston, MA 02118, USA; Boston University School of Public Health, 715 Albany Street, Talbot Building, Boston, MA 02118, USA; Boston Medical Center, 850 Harrison Ave, Dowling 3N, Boston, MA 02118, USA. Electronic address: Benjamin.linas@bmc.org.
Judith I TsuiBoston Medical Center, 850 Harrison Ave, Dowling 3N, Boston, MA 02118, USA. Electronic address: tsuij@uw.edu.
Boston University · USBoston Medical Center · US

Funding

Translational ScienceP30AI042853 · NIAID · MIRIAM HOSPITAL · PI LARRY K BROWN · 1998 to 2026
$51.7M
Utilization of health services after engagement with opioid use disorder (OUD) treatment provider by individuals with and without post-traumatic stress disorderP30DA040500 · NIDA · WEILL MEDICAL COLL OF CORNELL UNIV · PI Benjamin P. Linas · 2015 to 2026
$20.7M
Clinical Addiction Research and Education ProgramR25DA013582 · NIDA · BOSTON MEDICAL CENTER · PI JEFFREY H. SAMET, Alexander Yale Walley · 2001 to 2026
$8.9M
Simulation Modeling to Improve HIV/HCV Screening, Treatment and CareR01DA031059 · NIDA · BOSTON MEDICAL CENTER · PI LINAS, BENJAMIN P. · 2012 to 2015
$2.1M
HCV and Pain in Substance Users With and Without HIVK23DA027367 · NIDA · BOSTON MEDICAL CENTER · PI TSUI, JUDITH · 2010 to 2013
$651k
NIAID NIH HHS P30 AI042853NIDA NIH HHS K23 DA027367NIDA NIH HHS P30 DA040500NIDA NIH HHS R01 DA031059NIDA NIH HHS R25 DA013582
6 · The paper itself

Abstract

aimsIn the United States, hepatitis C virus (HCV) infection is primarily spread through injection drug use. There is an urgent need to improve access to care for HCV among persons with opioid use disorders who inject drugs. The purpose of our study was to determine the prevalence of HCV, patient characteristics, and receipt of appropriate care in a sample of patients treated with buprenorphine for their opioid use disorders in a primary care setting.

methodsThis study used retrospective clinical data from the electronic medical record. The study population included patients receiving buprenorphine in the Office Based Opioid Treatment (OBOT) clinic within the adult primary medicine clinic at Boston Medical Center between October 2003 and August 2013 who received a conclusive HCV antibody (Ab) test within a year of clinic entry. We compared characteristics by HCV serostatus using Pearson's chi-square and provided numbers/percentages receiving appropriate care.

resultsThe sample comprised 700 patients. Slightly less than half of all patients (n=334, 47.7%) were HCV Ab positive, and were significantly more likely to be older, Hispanic or African American, have diagnoses of post-traumatic stress disorder (PTSD) or bipolar disorder, have prior heroin or cocaine use, and be HIV-infected. Among the 334 HCV Ab positive patients, 226 (67.7%) had detectable HCV ribonucleic acid (RNA) indicating chronic HCV infection; only 5 patients (2.21%) with chronic HCV infection ever initiated treatment.

conclusionsNearly half of patients (47.7%) receiving office-based treatment with buprenorphine for their opioid use disorder had a positive hepatitis C virus antibody screening test although initiation of HCV treatment was nearly non-existent (2.21%).

Indexed as

AdultBostonBuprenorphineFemaleHepatitis CHepatitis C AntibodiesHumansMaleMiddle AgedOpiate Substitution TreatmentOpioid-Related DisordersPrevalencePrimary Health CareRetrospective StudiesRisk FactorsSubstance Abuse, IntravenousBuprenorphineHepatitis C AntibodiesBuprenorphineHCV screeningHCV treatmentOpioid agonist therapy

Identifiers

PMID26988423
PMCPMC5097249
OpenAlexW2252940432

What OpenQuestion holds

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LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.