ArticleBehavioural brain research2016
Higher rate alternative non-drug reinforcement produces faster suppression of cocaine seeking but more resurgence when removed.
Article in Behavioural brain research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
23 citing papers in PubMed.
- Oxycodone self-administration and drug-primed responding in male and female squirrel monkeys: Effects of alternative reinforcer availability.The Journal of pharmacology and experimental therapeutics · 2025Article
- The extinction burst: Effects of alternative reinforcement magnitude.Journal of the experimental analysis of behavior · 2025Article
- Resurgence and Behavioral Contrast, Compared and Contrasted.Perspectives on behavior science · 2024Article
- Resurgence Following Higher or Lower Quality Alternative Reinforcement.Journal of the experimental analysis of behavior · 2024Article
- Translational evaluation of on/off alternative reinforcement cycling.Journal of the experimental analysis of behavior · 2023Article
- Relapse and its mitigation: Toward behavioral inoculation.Journal of applied behavior analysis · 2023Review
- A Comprehensive Systematic Review of Procedures and Analyses Used in Basic and Preclinical Studies of Resurgence, 1970-2020.Perspectives on behavior science · 2023Review
- Nondrug reinforcers contingent on alternative behavior or abstinence increase resistance to extinction and reinstatement of ethanol-maintained behavior.Journal of the experimental analysis of behavior · 2022Article
- ABA from A to Z: Behavior Science Applied to 350 Domains of Socially Significant Behavior.Perspectives on behavior science · 2022Article
- Examination of alternative-response discrimination training and resurgence in rats.Learning & behavior · 2021Article
- The extinction burst: Impact of reinforcement time and level of analysis on measured prevalence.Journal of the experimental analysis of behavior · 2021Article
- BEHAVIORAL AND NEUROBIOLOGICAL MECHANISMS OF PAVLOVIAN AND INSTRUMENTAL EXTINCTION LEARNING.Physiological reviews · 2021Review
- Resurgence and repeated within-session progressive-interval thinning of alternative reinforcement.Journal of the experimental analysis of behavior · 2021Article
- Resurgence and downshifts in alternative reinforcement rate.Journal of the experimental analysis of behavior · 2020Article
- Resurgence of punishment-suppressed cocaine seeking in rats.Experimental and clinical psychopharmacology · 2020Article
- Changes in the elimination and resurgence of alcohol-maintained behavior in rats and the effects of naltrexone.Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors · 2020Article
- Cues Associated with Alternative Reinforcement During Extinction Can Attenuate Resurgence of an Extinguished Instrumental Response.Learning & behavior · 2019Article
- Longer treatment with alternative non-drug reinforcement fails to reduce resurgence of cocaine or alcohol seeking in rats.Behavioural brain research · 2018Article
- Resurgence as Choice.Behavioural processes · 2017Review
- Preventing relapse after incentivized choice treatment: A laboratory model.Behavioural processes · 2017Review
Corrections and comments
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Authors and funding
4 authors.
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Abstract
Relapse following removal of an alternative source of reinforcement introduced during extinction of a target behavior is called resurgence. This form of relapse may be related to relapse of drug taking following loss of alternative non-drug reinforcement in human populations. Laboratory investigations of factors mediating resurgence with food-maintained behavior suggest higher rates of alternative reinforcement produce faster suppression of target behavior but paradoxically generate more relapse when alternative reinforcement is discontinued. At present, it is unknown if a similar effect occurs when target behavior is maintained by drug reinforcement and the alternative is a non-drug reinforcer. In the present experiment three groups of rats were trained to lever press for infusions of cocaine during baseline. Next, during treatment, cocaine reinforcement was suspended and an alternative response was reinforced with either high-rate, low-rate, or no alternative food reinforcement. Finally, all reinforcement was suspended to test for relapse of cocaine seeking. Higher rate alternative reinforcement produced faster elimination of cocaine seeking than lower rates or extinction alone, but when treatment was suspended resurgence of cocaine seeking occurred following only high-rate alternative reinforcement. Thus, although higher rate alternative reinforcement appears to more effectively suppress drug seeking, should it become unavailable, it can have the unfortunate effect of increasing relapse.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.