ReviewJournal of cellular and molecular medicine2016
Ambient particulate matter exposure and cardiovascular diseases: a focus on progenitor and stem cells.
Review in Journal of cellular and molecular medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 41 citations in OpenAlex.
- Senolytics Reverse PMCardiovascular toxicology · 2026Article
- Exposure to air pollution and cardiovascular risk in young children - a pilot project.Pediatric research · 2024Article
- N-Acetylcysteine and Atherosclerosis: Promises and Challenges.Antioxidants (Basel, Switzerland) · 2023Review
- Effects of Gallic Acid on Memory Deficits and Electrophysiological Impairments Induced by Cerebral Ischemia/Reperfusion in Rats Following Exposure to Ambient Dust Storm.Neurochemical research · 2023Article
- Associations between ambient air pollution, obesity, and serum vitamin D status in the general population of Korean adults.BMC public health · 2022Article
- N‑acetyl cysteine prevents ambient fine particulate matter‑potentiated atherosclerosis via inhibition of reactive oxygen species‑induced oxidized low density lipoprotein elevation and decreased circulating endothelial progenitor cell.Molecular medicine reports · 2022Article
- Air Pollution Exposure Induces Vascular Injury and Hampers Endothelial Repair by Altering Progenitor and Stem Cells Functionality.Frontiers in cell and developmental biology · 2022Review
- Isosinensetin alleviates the injury of human bronchial epithelial cells induced by PMExperimental and therapeutic medicine · 2021Article
- The critical role of endothelial function in fine particulate matter-induced atherosclerosis.Particle and fibre toxicology · 2020Review
- N-acetylcysteine differentially regulates the populations of bone marrow and circulating endothelial progenitor cells in mice with limb ischemia.European journal of pharmacology · 2020Article
- Oxidative stress and the cardiovascular effects of air pollution.Free radical biology & medicine · 2020Review
- Alpha-tocopherol exerts protective function against the mucotoxicity of particulate matter in amphibian and human goblet cells.Scientific reports · 2020Article
- Impact of Commuting Mode on Obesity Among a Working Population in Beijing, China: Adjusting for Air Pollution.Diabetes, metabolic syndrome and obesity : targets and therapy · 2020Article
- Extracorporeal cardiac shock waves therapy promotes function of endothelial progenitor cells through PI3K/AKT and MEK/ERK signaling pathways.American journal of translational research · 2020Article
- Concomitant overexpression of triple antioxidant enzymes selectively increases circulating endothelial progenitor cells in mice with limb ischaemia.Journal of cellular and molecular medicine · 2019Article
- Probucol protects circulating endothelial progenitor cells from ambient PMExperimental and therapeutic medicine · 2018Article
- Article
- Low serum vitamin D-status, air pollution and obesity: A dangerous liaison.Reviews in endocrine & metabolic disorders · 2017Review
- Predictive and Prognostic Biomarkers of Respiratory Diseases due to Particulate Matter Exposure.Journal of cancer prevention · 2017Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
Air pollution is a major challenge to public health. Ambient fine particulate matter (PM) is the key component for air pollution, and associated with significant mortality. The majority of the mortality following PM exposure is related to cardiovascular diseases. However, the mechanisms for the adverse effects of PM exposure on cardiovascular system remain largely unknown and under active investigation. Endothelial dysfunction or injury is considered one of the major factors that contribute to the development of cardiovascular diseases such as atherosclerosis and coronary heart disease. Endothelial progenitor cells (EPCs) play a critical role in maintaining the structural and functional integrity of vasculature. Particulate matter exposure significantly suppressed the number and function of EPCs in animals and humans. However, the mechanisms for the detrimental effects of PM on EPCs remain to be fully defined. One of the important mechanisms might be related to increased level of reactive oxygen species (ROS) and inflammation. Bone marrow (BM) is a major source of EPCs. Thus, the number and function of EPCs could be intimately associated with the population and functional status of stem cells (SCs) in the BM. Bone marrow stem cells and other SCs have the potential for cardiovascular regeneration and repair. The present review is focused on summarizing the detrimental effects of PM exposure on EPCs and SCs, and potential mechanisms including ROS formation as well as clinical implications.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.