ReviewNutrition journal2016
Beta-palmitate - a natural component of human milk in supplemental milk formulas.
Review in Nutrition journal, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
32 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Total Fat and Fatty Acid Composition of Preterm Human Milk: A Systematic Review and Meta-analysis.Advances in nutrition (Bethesda, Md.) · 2026Pooled it
- A young child formula with Limosilactobacillus reuteri and GOS modulates gut microbiome and enhances bone and muscle development: a randomized trial.Nature communications · 2025Trial
- A novel human milk fortifier supports adequate growth in very low birth weight infants: a non-inferiority randomised controlled trial.Archives of disease in childhood. Fetal and neonatal edition · 2025Trial
- No effect of adding dairy lipids or long chain polyunsaturated fatty acids on formula tolerance and growth in full term infants: a randomized controlled trial.BMC pediatrics · 2018Trial
- Changes in fatty acid profiles of transition milk of Czech Fleckvieh cows milked in automatic milking system.Veterinary and animal science · 2026Article
- Comparative Analysis of Signature Lipid Structures in Canine and Feline Milk Compared with Bovine and Caprine Milk.Animals : an open access journal from MDPI · 2026Article
- Fatty Acid Profile, Lipid Quality Indices and Oxidative Stability of Snacks Consumed by Children Aged 6-24 Months in Rural Matiari, Sindh, Pakistan.Foods (Basel, Switzerland) · 2025Article
- Growth and gastrointestinal tolerance of healthy formula-fed infants: a multicentre, prospective observational study.BMC pediatrics · 2025Observational
- Observational
- Observational
- Development and large-scale production of human milk fat analog by fermentation of microalgae.Frontiers in nutrition · 2024Article
- Safety evaluation of INFAT® PLUS: Acute, genetic, teratogenic, and subchronic (90-day) toxicity studies.Toxicology reports · 2023Article
- Direct effect of 2-palmitoyl glycerol on promotion of gamma aminobutyric acid synthesis in normal human fetal-derived astrocytes.FEBS open bio · 2023Article
- Progress of Mass Spectrometry-Based Lipidomics in the Dairy Field.Foods (Basel, Switzerland) · 2023Review
- The Impact of Linoleic Acid on Infant Health in the Absence or Presence of DHA in Infant Formulas.Nutrients · 2023Review
- Ostrich oil as a fat substitute in milk-based infant formula.Food science & nutrition · 2023Article
- A new frontier for fat: dietary palmitic acid induces innate immune memory.Immunometabolism (Cobham, Surrey) · 2023Review
- Lipid Profiles of Human Milk and Infant Formulas: A Comparative Lipidomics Study.Foods (Basel, Switzerland) · 2023Article
- Evaluation of Fatty Acid Distributions and Triacylglycerol Species in Sow Milk and Commercial Piglet Formulas: A Comparative Study Based on Fat Sources and Lactation Stages.Animals : an open access journal from MDPI · 2022Article
- Spectral Analysis and Antiulcer Potential ofLife (Basel, Switzerland) · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The composition and function of human milk is unique and gives a basis for the development of modern artificial milk formulas that can provide an appropriate substitute for non-breastfed infants. Although human milk is not fully substitutable, modern milk formulas are attempting to mimic human milk and partially substitute its complex biological positive effects on infants. Besides the immunomodulatory factors from human milk, research has been focused on the composition and structure of human milk fat with a high content of β-palmitic acid (sn-2 palmitic acid, β-palmitate). According to the available studies, increasing the content of β-palmitate added to milk formulas promotes several beneficial physiological functions. β-palmitate positively influences fatty acid metabolism, increases calcium absorption, improves bone matrix quality and the stool consistency, and has a positive effect on the development of the intestinal microbiome.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.