ArticleJournal of cellular and molecular medicine2016
Telocytes in exercise-induced cardiac growth.
Article in Journal of cellular and molecular medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed.
- Exercise intensity-dependent cardiac telocyte expansion is associated with physiological growth despite JAK/STAT pathway inactivity in male Wistar rats.Experimental physiology · 2026Article
- Different types of exercise and myocardial angiogenesis regulation: A scoping review of cardiac-specific evidence in animal models.Physiological reports · 2026Article
- Elucidating the preventive and therapeutic effects of cardiac telocytes paracrine microRNAs on ischemic heart disease.Frontiers in cardiovascular medicine · 2025Article
- Modified mRNA-MediatedInternational journal of molecular sciences · 2024Article
- Identification and protective role of CD34Histochemistry and cell biology · 2023Article
- Telocytes response to cardiac growth induced by resistance exercise training and endurance exercise training in adult male rats.The journal of physiological sciences : JPS · 2023Article
- Morphological Evidence of Telocytes in Skeletal Muscle Interstitium of Exercised and Sedentary Rodents.Biomedicines · 2021Article
- The "Angiogenic Switch" and Functional Resources in Cyclic Sports Athletes.International journal of molecular sciences · 2021Review
- Morpho-functional changes of cardiac telocytes in isolated atrial amyloidosis in patients with atrial fibrillation.Scientific reports · 2021Article
- Energy Metabolism in Exercise-Induced Physiologic Cardiac Hypertrophy.Frontiers in pharmacology · 2020Review
- Early moderate exercise benefits myocardial infarction healing via improvement of inflammation and ventricular remodelling in rats.Journal of cellular and molecular medicine · 2019Article
- Expression of toll-like receptors and their regulatory roles in murine cardiac telocytes.Journal of cellular and molecular medicine · 2019Article
- Article
- Cardiac cell proliferation is not necessary for exercise-induced cardiac growth but required for its protection against ischaemia/reperfusion injury.Journal of cellular and molecular medicine · 2017Article
- Telocytes: a potential defender in the spleen of Npc1 mutant mice.Journal of cellular and molecular medicine · 2017Article
- Article
- Telocytes and Their Extracellular Vesicles-Evidence and Hypotheses.International journal of molecular sciences · 2016Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Exercise can induce physiological cardiac growth, which is featured by enlarged cardiomyocyte cell size and formation of new cardiomyocytes. Telocytes (TCs) are a recently identified distinct interstitial cell type, existing in many tissues and organs including heart. TCs have been shown to form a tandem with cardiac stem/progenitor cells in cardiac stem cell niches, participating in cardiac regeneration and repair. Although exercise-induced cardiac growth has been confirmed as an important way to promote cardiac regeneration and repair, the response of cardiac TCs to exercise is still unclear. In this study, 4 weeks of swimming training was used to induce robust healthy cardiac growth. Exercise can induce an increase in cardiomyocyte cell size and formation of new cardiomyocytes as determined by Wheat Germ Lectin and EdU staining respectively. TCs were identified by three immunofluorescence stainings including double labelling for CD34/vimentin, CD34/platelet-derived growth factor (PDGF) receptor-α and CD34/PDGF receptor-β. We found that cardiac TCs were significantly increased in exercised heart, suggesting that TCs might help control the activity of cardiac stem/progenitor cells, cardiomyocytes or endothelial cells. Adding cardiac TCs might help promote cardiac regeneration and renewal.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.