ReviewCNS oncology2016
Fatigue among patients with brain tumors.
Review in CNS oncology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
35 citing papers in PubMed, 2 syntheses or guidelines pooled it, 75 citations in OpenAlex.
- Predictors of functional outcomes in adults with brain tumor undergoing rehabilitation treatment: a systematic review.European journal of physical and rehabilitation medicine · 2022Pooled it
- Employment and Work Ability of Persons With Brain Tumors: A Systematic Review.Frontiers in human neuroscience · 2020Pooled it
- Bayesian adaptive randomized trial of blended cognitive behavioral therapy for severe fatigue in stable diffuse glioma.Neuro-oncology · 2026Trial
- Significant aggravation of pre-existing myalgic encephalomyelitis/chronic fatigue syndrome following proton beam therapy for sphenoid wing meningioma: case report.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2026Article
- "Such a different type of tiredness": people with brain tumour, their caregivers', and healthcare professionals' qualitative perceptions of cancer-related fatigue.Journal of cancer survivorship : research and practice · 2026Article
- The impact of neighborhood-level disadvantage on symptoms, mood, and health-related quality of life among the primary brain tumor population.Neuro-oncology practice · 2026Article
- Construction and internal assessment of an exploratory risk prediction model for psychological distress in brain tumor patients: a cross-sectional study.BMC cancer · 2026Article
- Socioeconomic disparities in patient-reported outcomes, health literacy, and access to care among patients with primary brain tumors: findings from the All of Us Research Program.Journal of neuro-oncology · 2025Article
- Construction and validation of a risk prediction model for symptom cluster distress in brain tumor patients: a cross-sectional study.BMC cancer · 2025Article
- Instruments for measuring fatigue in patients with brain tumours: protocol for a COSMIN--based systematic review.BMJ open · 2025Article
- Rehabilitation nursing for brain tumor patients: a scoping review.BMC medical education · 2025Article
- Co-designing a web-based intervention (RESTORE) to support self-management of cancer-related fatigue in people living with a brain tumour.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025Article
- Chronic Neurological Complications of Brain Tumors and Brain Tumor Treatments.Current neurology and neuroscience reports · 2025Review
- An Overview of Reviews on Predictors of Neurorehabilitation in Surgical or Non-Surgical Patients with Brain Tumours.Life (Basel, Switzerland) · 2024Review
- Age-independent benefits of postoperative rehabilitation during chemoradiotherapy on functional outcomes and survival in patients with glioblastoma.Journal of neuro-oncology · 2024Article
- Establishing the minimal clinically important difference of the Brief Fatigue Inventory for brain or CNS cancer patients undergoing radiotherapy.Neuro-oncology practice · 2024Article
- Postsurgical motor function and processing speed as predictors of quality of life in patients with chronic-phase glioblastoma.Acta neurochirurgica · 2024Article
- Understanding the association between fatigue and neurocognitive functioning in patients with glioma: A cross-sectional multinational study.Neuro-oncology practice · 2024Article
- Non-pharmacological fatigue interventions for patients with a primary brain tumour: a scoping review protocol.BMJ open · 2023Article
- Palliative Care in Neuro-oncology: an Update.Current neurology and neuroscience reports · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Fatigue is a ubiquitous and an extremely distressing symptom among patients with brain tumors (BT), particularly those with high-grade gliomas. The pathophysiology of cancer-related fatigue (CRF) in the context of patients with BT is multifactorial and complex, involving biological, behavioral, medical and social factors. The etiology of CRF in the general oncology population is pointing to the role of inflammatory cytokines as a key factor in the genesis of CRF, but this research is currently limited in the setting of BT. CRF should be screened, assessed and managed according to clinical practice guidelines. Fatigue has recently emerged as a strong, independent prognostic factor for survival that provides incremental prognostic value to the traditional markers of prognosis in recurrent high-grade gliomas. Therefore, strategies to treat fatigue warrant investigation, not only to improve the QOL of a group of patients with often limited life expectancy, but also possibly to optimize survival.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.