SynthesisPloS one2016
Failure of Passive Immune Transfer in Calves: A Meta-Analysis on the Consequences and Assessment of the Economic Impact.
Synthesis in PloS one, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 70 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
70 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Systematic Review and Meta-Analysis of Diagnostic Accuracy of Serum Refractometry and Brix Refractometry for the Diagnosis of Inadequate Transfer of Passive Immunity in Calves.Journal of veterinary internal medicine · 2018Pooled it
- Assessment of current colostrum feeding practices and passive transfer of immunity in dairy herds in Great Britain: A cross-sectional study.The Veterinary record · 2026Article
- Determination of risk factors for neonatal calf diarrhea using survival analysis.Tropical animal health and production · 2026Article
- Comparison of the Effectiveness of Colostrum, Colostrum Powder and Combined Feeding on Transfer of Passive Immunity in Calves.Veterinary medicine and science · 2026Article
- Impact of Dam Lactation Number on Colostrum Quality, Calf Growth, and Economic Performance in Holstein Cows.Veterinary sciences · 2026Article
- Mapping Variability in Bovine Respiratory Disease Risk Factors in Beef Production Systems: A Scoping Review.Animals : an open access journal from MDPI · 2026Review
- Short communication: Performance evaluation of beef calves fed different levels of colostrum replacer in tropical conditions.Veterinary and animal science · 2026Article
- Inter-rater agreement of a newborn calf lung ultrasound scoring system.Journal of veterinary internal medicine · 2026Article
- Influence of ewe metabolic status on failure of passive transfer of immunity and lamb production in a UK lowland flock.The Veterinary record · 2025Article
- Passive Immunity Establishment Through Colostral IgG Absorption in Neonatal Ruminants: Foundation for Efficient Ruminant Production.Animals : an open access journal from MDPI · 2025Review
- Main Husbandry Practices and Health Conditions That Affect Welfare in Calves: A Narrative Review.Animals : an open access journal from MDPI · 2025Review
- Multiblock Analysis of Risk Factors and Management Areas of Calf Mortality in Large-Scale Dairy Herds.Animals : an open access journal from MDPI · 2025Article
- Failure of Passive Immune Transfer in Neonatal Beef Calves: A Scoping Review.Animals : an open access journal from MDPI · 2025Review
- Welfare of beef cattle.EFSA journal. European Food Safety Authority · 2025Article
- What can't colostrum do? Exploring the effects of supplementing colostrum after the first day of life: A narrative review.JDS communications · 2025Article
- Temporal establishment of the colon microbiota in Angus calves from birth to post-weaning.PloS one · 2025Article
- Impact of Host and Management Factors on Calf Morbidity and Mortality Rates in Smallholder Dairy Farms in Central Ethiopia: A Prospective Cohort Study.Veterinary medicine international · 2025Article
- Factors associated with failure of passive transfer of immunity and morbidity in spring-born beef and dairy calves during the first 30 days of life.Frontiers in veterinary science · 2025Article
- Estimated breeding values of dairy sires for cow colostrum and transfer of passive immunity traits.JDS communications · 2025Article
- Evaluation of factors associated with immunoglobulin, protein, fat and lactose concentrations in colostrum of dairy cows from Austria.Acta veterinaria Scandinavica · 2024Article
10 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Low colostrum intake at birth results in the failure of passive transfer (FPT) due to the inadequate ingestion of colostral immunoglobulins (Ig). FPT is associated with an increased risk of mortality and decreased health and longevity. Despite the known management practices associated with low FPT, it remains an important issue in the field. Neither a quantitative analysis of FPT consequences nor an assessment of its total cost are available. To address this point, a meta-analysis on the adjusted associations between FPT and its outcomes was first performed. Then, the total costs of FPT in European systems were calculated using a stochastic method with adjusted values as the input parameters. The adjusted risks (and 95% confidence intervals) for mortality, bovine respiratory disease, diarrhoea and overall morbidity in the case of FPT were 2.12 (1.43-3.13), 1.75 (1.50-2.03), 1.51 (1.05-2.17) and 1.91 (1.63-2.24), respectively. The mean (and 95% prediction interval) total costs per calf with FPT were estimated to be €60 (€10-109) and €80 (€20-139) for dairy and beef, respectively. As a result of the double-step stochastic method, the proposed economic estimation constitutes the first estimate available for FPT. The results are presented in a way that facilitates their use in the field and, with limited effort, combines the cost of each contributor to increase the applicability of the economic assessment to the situations farm-advisors may face. The present economic estimates are also an important tool to evaluate the profitability of measures that aim to improve colostrum intake and FPT prevention.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.