Evidence map›Paper›PMID 26985451›Full record

ArticleRegenerative engineering and translational medicine2015

REGENERATIVE ENGINEERING: APPROACHES TO LIMB REGENERATION AND OTHER GRAND CHALLENGES.

Cato T Laurencin, Lakshmi S Nair

Open access · bronzeAbstract read
In one paragraph

Article in Regenerative engineering and translational medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it, 51 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Hyaluronic acid-British anti-Lewisite as a safer chelation therapy for the treatment of arthroplasty-related metallosis.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  4. Bioprinting Technologies and Bioinks for Vascular Model Establishment.International journal of molecular sciences · 2023
    Review
  5. Review
  6. Stromal Vascular Fraction for Osteoarthritis of the Knee Regenerative Engineering.Regenerative engineering and translational medicine · 2022
    Article
  7. Regenerative Engineering Animal Models for Knee Osteoarthritis.Regenerative engineering and translational medicine · 2022
    Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Review
  13. Bioinspired Scaffold Designs for Regenerating Musculoskeletal Tissue Interfaces.Regenerative engineering and translational medicine · 2020
    Article
  14. Article
  15. Article
  16. Regenerative Cell-Based Therapies: Cutting Edge, Bleeding Edge, and Off the Edge.Regenerative engineering and translational medicine · 2020
    Article
  17. Article
  18. Skeletal Muscle Regenerative Engineering.Regenerative engineering and translational medicine · 2019
    Article
  19. Biodegradable Polyphosphazene-Based Blends for Regenerative Engineering.Regenerative engineering and translational medicine · 2017
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Cato T LaurencinDepartment of Orthopaedic Surgery; Institute for Regenerative Engineering; Raymond and Beverly Sackler Center for Biomedical, Biological, Physical and Engineering Sciences; University of Connecticut Health Center, Farmington, CT 06030, USA; Department of Biomedical Engineering; Department of Materials Science and Engineering, Storrs, CT 06269, USA; Department of Chemical and Biomolecular Engineering University of Connecticut, Storrs, CT 06269, USA.
Lakshmi S NairDepartment of Orthopaedic Surgery; Institute for Regenerative Engineering; Raymond and Beverly Sackler Center for Biomedical, Biological, Physical and Engineering Sciences; University of Connecticut Health Center, Farmington, CT 06030, USA; Department of Biomedical Engineering; Department of Materials Science and Engineering, Storrs, CT 06269, USA.
University of Connecticut · US

Funding

Regenerative Engineering of Complex Musculoskeletal Tissues and JointsDP1AR068147 · NIAMS · UNIVERSITY OF CONNECTICUT SCH OF MED/DNT · PI LAURENCIN, CATO T. · 2014 to 2018
$4.1M
NIAMS NIH HHS DP1 AR068147
6 · The paper itself

Abstract

The clinical grand challenge to regenerate complex tissue and organ systems call for a paradigm shift that requires a transdisciplinary approach. The field of regenerative engineering puts forward a Convergence approach to create a regenerative toolbox to move beyond individual tissue repair to the regeneration of complex tissues and organ systems. Here we discuss the regenerative tool box currently under development to address grand opportunities in complex tissue/organ regeneration.

Identifiers

PMID26985451
PMCPMC4789288
OpenAlexW2299514119

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.