ReviewJournal of family medicine and primary care
Diagnosis and management of preeclampsia in community settings in low and middle-income countries.
Review in Journal of family medicine and primary care. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06413576 (The Clinical Utility of Homocysteine in Critically Ill Preeclampsia Patients), which is not on this map. Cited by 37 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Clinical Utility of Homocysteine in Critically Ill Preeclampsia Patients
Who cites it
37 citing papers in PubMed, 2 syntheses or guidelines pooled it, 73 citations in OpenAlex.
- Predictive accuracy of ophthalmic artery Doppler for pre-eclampsia: a systematic review.BMJ open · 2025Pooled it
- Prevalence and determinants of hypertensive disorders of pregnancy in Ethiopia: A systematic review and meta-analysis.PloS one · 2020Pooled it
- Development of antenatal risk prediction model for preeclampsia with severe features in Lagos, Nigeria (PreSev study): protocol of a prospective cohort study.BMC pregnancy and childbirth · 2026Article
- Machine Learning for Dynamic and Short-Term Prediction of Preeclampsia Using Routine Clinical Data.JAMA network open · 2026Article
- A randomized controlled trial of N-acetylcysteine in the treatment of early-onset preeclampsia: Study Protocol.PloS one · 2026Article
- Evaluation of Serum Lactate Dehydrogenase and Electrolyte Levels Among Preeclamptic Women at the University of Gondar Comprehensive Specialized Hospital, Northwest, Ethiopia: A Comparative Cross-Sectional Study.Journal of pregnancy · 2026Article
- Diagnostic Concordance and Misclassification of Pre-Eclampsia in a Malaria-Endemic Setting: A Comparative Cross-Sectional Study.BioMed research international · 2026Article
- Development of a Risk Score for the Prediction and Management of Pre-Eclampsia in Low-Resource Settings.Journal of clinical medicine · 2025Article
- An Increased Plasma D-Dimer Levels During Different Stages of Normal and Complicated Pregnancies Among Women in Bisha, Saudi Arabia.Journal of blood medicine · 2025Article
- Health Impacts of Pre-eclampsia: A Comprehensive Analysis of Maternal and Neonatal Outcomes.Medicina (Kaunas, Lithuania) · 2024Observational
- Pre-referral management of preeclampsia with severity features in a low-income country-characteristics and challenges in a Sub-Saharan setting: a mixed method study.AJOG global reports · 2024Article
- Detection of Urinary Misfolded Proteins for Imminent Prediction of Preeclampsia in Pregnant Women With Suspected Cases: Protocol for a Prospective Noninterventional Study.JMIR research protocols · 2024Article
- AI-based preeclampsia detection and prediction with electrocardiogram data.Frontiers in cardiovascular medicine · 2024Article
- Predicting place of delivery choice among childbearing women in East Africa: a comparative analysis of advanced machine learning techniques.Frontiers in public health · 2024Article
- Vulnerabilities and reparative strategies during pregnancy, childbirth, and the postpartum period: moving from rhetoric to action.EClinicalMedicine · 2024Review
- Awareness of Preeclampsia and Its Associated Factors Among Women in Al Baha Region, Saudi Arabia.Cureus · 2023Article
- Association between endothelial nitric oxide synthase (eNOS) gene variants and nitric oxide production in preeclampsia: a case-control study in Ghana.Scientific reports · 2023Article
- Postpartum resolution of hypertension, proteinuria and acute kidney injury among women with preeclampsia and severe features at Mulago National Referral Hospital, Uganda: a cohort study.African health sciences · 2023Article
- Magnetic resonance spectroscopy and liquid chromatography-mass spectrometry metabolomics study may differentiate pre-eclampsia from gestational hypertension.European radiology · 2023Article
- A socioecological description of the influencing factors to midwives' management of preeclampsia in a Ghanaian tertiary hospital.PloS one · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Hypertensive disorders of pregnancy contribute significantly to maternal mortality and morbidity. Preeclampsia belongs to the spectrum of hypertensive disorders of pregnancy and if undiagnosed and/or untreated leads to fatal consequences for both the mother and the baby. Early detection and prevention of preeclampsia is limited by uncertainty in the knowledge about its etiopathogenesis. While much work has been done in establishing clinical guidelines for management of preeclampsia in the hospital or tertiary care settings, there is considerable lack of work in the domain of evidence-based guidelines for screening, identification and management of preeclampsia at the community-level. The article reviews these issues with special considerations and to challenges faced in low and middle-income countries. There is a need to focus on low-cost screening and interventions in the community to achieve a significant impact on preventable maternal and fetal mortality in order to control the burden of preeclampsia significantly as well as investing on more research at primary care level to improve the evidence base for community-level interventions.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.