Evidence map›Paper›PMID 26985399›Full record

ArticleCurrent addiction reports2015

Designing Interventions Informed by Scientific Knowledge About Effects of Early Adversity: A Translational Neuroscience Agenda for Next Generation Addictions Research.

Philip A Fisher, Elliot T Berkman

2 registry-linked trialsOpen access · bronzeAbstract read
In one paragraph

Article in Current addiction reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.1field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02945371 nacompletednot on this map

Tailored Inhibitory Control Training to Reverse EA-linked Deficits in Mid-life

TypeinterventionalSponsorUniversity of OregonRan2014 to 2016Enrolled103ConditionsSmoking, Alcohol Drinking, Prescription Drug Abuse, Substance-Related DisordersArmsPerson-centered inhibitory control training, Active behavioral response training
NCT03557710 nacompletednot on this mapstarted 2018, after this paper: background citation

Devaluing Energy-dense Foods for Cancer-control: Translational Neuroscience

TypeinterventionalSponsorUniversity of OregonRan2018 to 2023Enrolled253ConditionsOverweight and Obesity, CancerArmsDevaluing energy-dense foods for cancer-control
3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Philip A FisherUniversity of Oregon.
Elliot T BerkmanUniversity of Oregon.

Funding

Project 3: The neurobiology of adverse early care in rhesus infants....P50MH078105 · NIMH · UNIVERSITY OF MINNESOTA · PI GUNNAR, MEGAN R · 2009 to 2013
$9.9M
Translational Drug Abuse Prevention CenterP50DA035763 · NIDA · OREGON SOCIAL LEARNING CENTER, INC. · PI CHAMBERLAIN, PATRICIA, FISHER, PHILIP A · 2013 to 2017
$9.5M
Randomized Trial of KEEP-P, a Preventive Intervention for Foster PreschoolersR01HD075716 · NICHD · UNIVERSITY OF OREGON · PI FISHER, PHILIP A · 2013 to 2017
$2.9M
Tailored inhibitory control training to reverse EA-linked deficits in mid-lifeR01AG048840 · NIA · UNIVERSITY OF OREGON · PI BERKMAN, ELLIOT TODD · 2014 to 2015
$670k
Reducing Craving for Cancer-promoting Foods Via Cognitive Self-regulationR21CA175241 · NCI · UNIVERSITY OF OREGON · PI BERKMAN, ELLIOT TODD · 2014 to 2015
$347k
NCI NIH HHS R21 CA175241NIA NIH HHS R01 AG048840NICHD NIH HHS R01 HD075716NIDA NIH HHS P50 DA035763NIMH NIH HHS P50 MH078105
6 · The paper itself

Abstract

In spite of extensive scientific knowledge about the neurobiological systems and neural pathways underlying addictions, only limited progress has been made to reduce the population-level incidence of addictions by using prevention and treatment programs. In this area of research the translation of basic neuroscience of causal mechanisms to effective interventions has not been fully realized. In this article we describe how an understanding of the effects of early adverse experiences on brain and biological development may provide new opportunities to achieve impact at scale with respect to reduction of addictions. We propose four categories of new knowledge that translational neuroscience investigations of addictions should incorporate to be successful. We then describe a translational neuroscience-informed smoking cessation intervention based on this model.

Indexed as

AddictionsEarly AdversityTranslational Neuroscience

Identifiers

PMID26985399
PMCPMC4789282
OpenAlexW1604713432

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.