Evidence map›Paper›PMID 26985398›Full record

ArticleOncoimmunology2015

Spatial separation of the processing and MHC class I loading compartments for cross-presentation of the tumor-associated antigen HER2/

Renato B Baleeiro, René Rietscher, Andrea Diedrich, Justyna A Czaplewska, Claus-Michael Lehr, Regina Scherließ, Andrea Hanefeld, Michael Gottschaldt, Peter Walden

Open access · goldAbstract read
In one paragraph

Article in Oncoimmunology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 12 citations in OpenAlex.

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  5. Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 1 country.

Renato B BaleeiroDepartment of Dermatology; Venerology and Allergology; Charité - Universitätsmedizin Berlin ; Berlin, Germany.
René RietscherHelmholtz Institute for Pharmaceutical Research Saarland (HIPS); Helmholtz Centre for Infection Research; Saarland University ; Saarbrücken, Germany.
Andrea DiedrichDepartment of Pharmaceutics and Biopharmaceutics; Kiel University ; Kiel, Germany.
Justyna A CzaplewskaLaboratory of Organic and Macromolecular Chemistry (IOMC); Friedrich Schiller University Jena; Jena, Germany; Jena Center for Soft Matter (JCSM); Friedrich Schiller University Jena; Jena, Germany.
Claus-Michael LehrHelmholtz Institute for Pharmaceutical Research Saarland (HIPS); Helmholtz Centre for Infection Research; Saarland University; Saarbrücken, Germany; Biopharmaceutics and Pharmaceutical Technology; Saarland University; Saarbrücken, Germany.
Regina ScherließDepartment of Pharmaceutics and Biopharmaceutics; Kiel University ; Kiel, Germany.
Andrea HanefeldOpen Innovation Management; Merck KGaA ; Darmstadt, Germany.
Michael GottschaldtLaboratory of Organic and Macromolecular Chemistry (IOMC); Friedrich Schiller University Jena; Jena, Germany; Jena Center for Soft Matter (JCSM); Friedrich Schiller University Jena; Jena, Germany.
Peter WaldenDepartment of Dermatology; Venerology and Allergology; Charité - Universitätsmedizin Berlin ; Berlin, Germany.
Charité - Universitätsmedizin Berlin · DEChristian-Albrechts-Universität zu Kiel · DEFriedrich Schiller University Jena · DEHelmholtz Centre for Infection Research · DEMerck (Germany) · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cross-presentation is the process by which professional antigen presenting cells (APCs) (B cells, dendritic cells (DCs) and macrophages) present endocytosed antigens (Ags) via MHC-I to CD8

Indexed as

cancercross-presentationdendritic cellsHER2/neunanoparticlestumor-associated antigensvaccine

Identifiers

PMID26985398
PMCPMC4792485
OpenAlexW1864630155

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.