ArticleClinical kidney journal2016
Atypical anti-glomerular basement membrane disease.
Article in Clinical kidney journal, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 38 citations in OpenAlex.
- Immune-complex-mediated membranoproliferative glomerulonephritis with linear IgG staining resembling atypical anti-glomerular basement membrane disease: a case report.CEN case reports · 2026Article
- Atypical Anti-glomerular Basement Membrane Disease in a 16-Year-Old Male Child: A Case Report.Cureus · 2025Article
- Clinical features and prognosis of patients with anti-GBM disease combined with mesangial IgA deposition.Frontiers in immunology · 2024Article
- Crescentic glomerulonephritis due to linear IgA anti-glomerular basement membrane disease: report of a rare case.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica · 2024Article
- A large-scale dataset of patient summaries for retrieval-based clinical decision support systems.Scientific data · 2023Article
- Atypical Anti-Glomerular Basement Membrane Disease.Kidney international reports · 2023Review
- Anti-GBM disease with positive serum anti-GBM antibodies but negative IgG deposition: A case report.SAGE open medical case reports · 2023Article
- Anti-glomerular basement membrane disease with IgA nephropathy: A case report.World journal of clinical cases · 2022Article
- Clinicopathological characteristics and predictors of poor outcome in anti-glomerular basement membrane disease - a fifteen year single center experience.Renal failure · 2021Observational
- Article
- Atypical anti-glomerular basement membrane disease complicated by methicillin-susceptible Staphylococcus aureus infection-related rapidly progressive glomerulonephritis: a case report and literature review.CEN case reports · 2021Review
- Anti-glomerular basement membrane disease and IgA nephropathy in a patient with previous renal cell carcinoma.BMJ case reports · 2021Article
- A Case of Glomerulopathy Associated With Monoclonal Glomerular Basement Membrane Antibody.Kidney international reports · 2021Article
- Atypical anti-glomerular basement membrane disease with anti-GBM antibody negativity and ANCA positivity: a case report.BMC nephrology · 2021Article
- Atypical Antiglomerular Basement Membrane Disease in a Pediatric Patient Successfully Treated with Rituximab.Case reports in nephrology · 2021Article
- Clinical-Pathological Features and Outcome of Atypical Anti-glomerular Basement Membrane Disease in a Large Single Cohort.Frontiers in immunology · 2020Article
- Atypical Anti-Glomerular Basement Membrane Disease With Diffuse Crescentic Membranoproliferative Glomerulonephritis: Case Report and Review of Literature.Qatar medical journal · 2020Article
- Concurrent Anti-glomerular Basement Membrane Nephritis and IgA Nephropathy.Journal of pathology and translational medicine · 2019Article
- Atypical Antiglomerular Basement Membrane Disease With IgG1-κ Staining.Kidney international reports · 2017Article
- Atypical anti-glomerular basement membrane disease: lessons learned.Clinical kidney journal · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAnti-glomerular basement membrane (anti-GBM) disease classically presents with aggressive necrotizing and crescentic glomerulonephritis, often with pulmonary hemorrhage. The pathologic hallmark is linear staining of GBMs for deposited immunoglobulin G (IgG), usually accompanied by serum autoantibodies to the collagen IV alpha-3 constituents of GBMs.
methodsRenal pathology files were searched for cases with linear anti-GBM to identify cases with atypical or indolent course. Histopathology, laboratory studies, treatment and outcome of those cases was reviewed in detail.
resultsFive anti-GBM cases with atypical clinicopathologic features were identified (accounting for ∼8% of anti-GBM cases in our laboratory). Kidney biopsies showed minimal glomerular changes by light microscopy; one patient had monoclonal IgG deposits in an allograft (likely recurrent). Three patients did not have detectable serum anti-GBM by conventional assays. Three patients had indolent clinical courses after immunosuppressive treatment. One patient, untreated after presenting with brief mild hematuria, re-presented after a short interval with necrotizing and crescentic glomerulonephritis.
conclusionsThorough clinicopathologic characterization and close follow-up of patients with findings of atypical anti-GBM on renal biopsy are needed. Review of the literature reveals only rare well-documented atypical anti-GBM cases to date, only one of which progressed to end-stage kidney disease.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.