ArticleACS medicinal chemistry letters2016
Astemizole Derivatives as Fluorescent Probes for hERG Potassium Channel Imaging.
Article in ACS medicinal chemistry letters, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- NBD-Based Environment-Sensitive Fluorescent Probes for the Human Ether-a-Go-Go-Related Gene Potassium Channel.Frontiers in molecular biosciences · 2021Article
- Article
- Aggregation-Induced Emission: Lighting Up hERG Potassium Channel.Frontiers in chemistry · 2019Article
- 3-D structural interactions and quantitative structural toxicity studies of tyrosine derivatives intended for safe potent inflammation treatment.Chemistry Central journal · 2016Article
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5 authors.
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Abstract
The detection and imaging of hERG potassium channels in living cells can provide useful information for hERG-correlation studies. Herein, three small-molecule fluorescent probes, based on the potent hERG channel inhibitor astemizole, for the imaging of hERG channels in hERG-transfected HEK293 cells (hERG-HEK293) and human colorectal cancer cells (HT-29), are described. These probes are expected to be applied in the physiological and pathological studies of hERG channels.
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