ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2016
Mirror Neurons of Ventral Premotor Cortex Are Modulated by Social Cues Provided by Others' Gaze.
Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
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Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.
- Systematic Comparison of Brain Imaging Meta-Analyses of ToM with vPT.BioMed research international · 2017Pooled it
- Reading out bodily cues to predict interactions.Scientific reports · 2025Article
- Depression in adolescence and young adulthood: the difficulty to integrate motivational/emotional systems.Frontiers in psychology · 2024Review
- Context expectation influences the gait pattern biomechanics.Scientific reports · 2023Article
- Building blocks of joint attention: Early sensitivity to having one's own gaze followed.Developmental cognitive neuroscience · 2019Article
- The role of the motor system in action understanding and communication: Evidence from human infants and non-human primates.Developmental psychobiology · 2019Review
- Grasping Neurons in the Ventral Premotor Cortex of Macaques Are Modulated by Social Goals.Journal of cognitive neuroscience · 2019Article
- Gaze and body cues interplay during interactive requests.PloS one · 2019Article
- Visual attention and action: How cueing, direct mapping, and social interactions drive orienting.Psychonomic bulletin & review · 2018Review
- Two different mirror neuron networks: The sensorimotor (hand) and limbic (face) pathways.Neuroscience · 2017Review
- Functional dissociation between anterior temporal lobe and inferior frontal gyrus in the processing of dynamic body expressions: Insights from behavioral variant frontotemporal dementia.Human brain mapping · 2016Article
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7 authors at 1 institution in 1 country.
Funding
Abstract
Mirror neurons (MNs) in the inferior parietal lobule and ventral premotor cortex (PMv) can code the intentions of other individuals using contextual cues. Gaze direction is an important social cue that can be used for understanding the meaning of actions made by other individuals. Here we addressed the issue of whether PMv MNs are influenced by the gaze direction of another individual. We recorded single-unit activity in macaque PMv while the monkey was observing an experimenter performing a grasping action and orienting his gaze either toward (congruent gaze condition) or away (incongruent gaze condition) from a target object. The results showed that one-half of the recorded MNs were modulated by the gaze direction of the human agent. These gaze-modulated neurons were evenly distributed between those preferring a gaze direction congruent with the direction where the grasping action was performed and the others that preferred an incongruent gaze. Whereas the presence of congruent responses is in line with the usual coupling of hand and gaze in both executed and observed actions, the incongruent responses can be explained by the long exposure of the monkeys to this condition. Our results reveal that the representation of observed actions in PMv is influenced by contextual information not only extracted from physical cues, but also from cues endowed with biological or social value. SIGNIFICANCE STATEMENT: In this study, we present the first evidence showing that social cues modulate MNs in the monkey ventral premotor cortex. These data suggest that there is an integrated representation of other's hand actions and gaze direction at the single neuron level in the ventral premotor cortex, and support the hypothesis of a functional role of MNs in decoding actions and understanding motor intentions.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.