ArticlePlant & cell physiology2016
Co-overexpressing a Plasma Membrane and a Vacuolar Membrane Sodium/Proton Antiporter Significantly Improves Salt Tolerance in Transgenic Arabidopsis Plants.
Article in Plant & cell physiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
27 citing papers in PubMed, 101 citations in OpenAlex.
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- Creating Climate-Resilient Crops by Increasing Drought, Heat, and Salt Tolerance.Plants (Basel, Switzerland) · 2024Review
- The Roles of Calcineurin B-like Proteins in Plants under Salt Stress.International journal of molecular sciences · 2023Review
- Plants' Response Mechanisms to Salinity Stress.Plants (Basel, Switzerland) · 2023Review
- A Salt-Tolerant Strain ofJournal of fungi (Basel, Switzerland) · 2023Article
- Genome-wide identification and expression analysis of theFrontiers in plant science · 2023Article
- Salt and Drought Stress Responses in Cultivated Beets (Plants (Basel, Switzerland) · 2021Review
- Improved yield, fruit quality, and salt resistance in tomato co-overexpressingPhysiology and molecular biology of plants : an international journal of functional plant biology · 2021Article
- Improving ATPase and PPase activities, nutrient uptake and growth of salt stressed ajowan plants by salicylic acid and iron-oxide nanoparticles.Plant cell reports · 2021Article
- A Review of Recent Advances and Future Directions in the Management of Salinity Stress in Finger Millet.Frontiers in plant science · 2021Review
- Genome-wide identification, characterization and transcriptional profiling of NHX-type (Na3 Biotech · 2021Article
- A Golgi-Localized Sodium/Hydrogen Exchanger Positively Regulates Salt Tolerance by Maintaining Higher KFrontiers in plant science · 2021Article
- NHX Gene Family inFrontiers in plant science · 2021Article
- Temporal salt stress-induced transcriptome alterations and regulatory mechanisms revealed by PacBio long-reads RNA sequencing in Gossypium hirsutum.BMC genomics · 2020Article
- Natural Genetic Resources from Diverse Plants to Improve Abiotic Stress Tolerance in Plants.International journal of molecular sciences · 2020Review
- Physiology and molecular biology of plants : an international journal of functional plant biology · 2020Article
- Overexpression of LeNHX4 improved yield, fruit quality and salt tolerance in tomato plants (Solanum lycopersicum L.).Molecular biology reports · 2020Article
- Global Landscapes of theInternational journal of molecular sciences · 2020Article
- Review
- Management of Plant Physiology with Beneficial Bacteria to Improve Leaf Bioactive Profiles and Plant Adaptation under Saline Stress inFoods (Basel, Switzerland) · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The Arabidopsis gene AtNHX1 encodes a vacuolar membrane-bound sodium/proton (Na(+)/H(+)) antiporter that transports Na(+) into the vacuole and exports H(+) into the cytoplasm. The Arabidopsis gene SOS1 encodes a plasma membrane-bound Na(+)/H(+) antiporter that exports Na(+) to the extracellular space and imports H(+) into the plant cell. Plants rely on these enzymes either to keep Na(+) out of the cell or to sequester Na(+) into vacuoles to avoid the toxic level of Na(+) in the cytoplasm. Overexpression of AtNHX1 or SOS1 could improve salt tolerance in transgenic plants, but the improved salt tolerance is limited. NaCl at concentration >200 mM would kill AtNHX1-overexpressing or SOS1-overexpressing plants. Here it is shown that co-overexpressing AtNHX1 and SOS1 could further improve salt tolerance in transgenic Arabidopsis plants, making transgenic Arabidopsis able to tolerate up to 250 mM NaCl treatment. Furthermore, co-overexpression of AtNHX1 and SOS1 could significantly reduce yield loss caused by the combined stresses of heat and salt, confirming the hypothesis that stacked overexpression of two genes could substantially improve tolerance against multiple stresses. This research serves as a proof of concept for improving salt tolerance in other plants including crops.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.