ArticleInteractive cardiovascular and thoracic surgery2016
The SYNTAX score is correlated with long-term outcomes of coronary artery bypass grafting for complex coronary artery lesions.
Article in Interactive cardiovascular and thoracic surgery, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
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Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.
- Percutaneous Coronary Intervention, Coronary Artery Bypass Surgery and the SYNTAX score: A systematic review and meta-analysis.Scientific reports · 2017Pooled it
- Impact of Coronary Endarterectomy on Mid-Term Left Ventricular Functional Recovery in Diffuse Coronary Artery Disease.Reviews in cardiovascular medicine · 2026Article
- Assessment of acute coronary syndromes among patients with left main coronary artery disease in centers with and without cardiac surgery on-site. Data from PL-ACS registry.Cardiology journal · 2025Article
- Coronary sodium [European journal of nuclear medicine and molecular imaging · 2024Observational
- Complexity of coronary artery disease and the release of cardiac biomarkers after CABG.Frontiers in cardiovascular medicine · 2024Article
- Coronary plaque burden predicts perioperative cardiovascular events after coronary endarterectomy.Frontiers in cardiovascular medicine · 2023Article
- Article
- Correlation between coronary CTAZhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2021Article
- Comparison of clinical outcomes after coronary artery bypass grafting using stratified SYNTAX scores.General thoracic and cardiovascular surgery · 2020Article
- Using the SYNTAX score to predict myocardial injury early after on-pump coronary artery bypass surgery: a single-centre experience analysis.Kardiochirurgia i torakochirurgia polska = Polish journal of cardio-thoracic surgery · 2020Article
- The Association of Syntax Score with Levels of Lipoprotein(a) and Inflammatory Biomarkers in Patients with Stable Coronary Artery Disease and Different Low-Density Lipoprotein Cholesterol Levels.Diabetes, metabolic syndrome and obesity : targets and therapy · 2020Article
- Adherence to guideline recommendations for coronary angiography in a poor South-East Asian setting: Impact on short- and medium-term clinical outcomes.Scientific reports · 2019Article
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesWe analysed retrospectively the long-term outcomes of conventional coronary artery bypass grafting (CABG) as employed routinely for complex coronary lesions by observing patients with low (0-22), intermediate (23-32) and high (≥33) SYNTAX scores. The purpose of this study was to evaluate the correlation between the SYNTAX score and long-term major adverse cardiac and cerebrovascular events (MACCEs) including all-cause death, stroke, myocardial infarction (MI) and repeat revascularization after CABG.
methodsThe study enrolled 396 consecutive patients with stable and untreated left main and/or three-vessel disease, who had been referred to our heart team from 2000 through 2009. They all routinely underwent conventional CABG. The three groups (low score; n = 159, intermediate score; n = 150, high score; n = 87) were compared, looking at the primary endpoint of MACCE and its components. We also analysed the effects of diverse variables on long-term MACCEs after the operation.
resultsThe cumulative 10-year MACCE rates in patients with low, intermediate and high SYNTAX score were 25.3, 35.8 and 48.1%, respectively. The Kaplan-Meier cumulative event curves showed a significantly higher MACCE rate after CABG in patients with a higher SYNTAX score than in those with a lower score (log-rank P = 0.0012). This was mainly because of a significantly increased rate of repeat revascularization in the higher SYNTAX score group (log-rank P = 0.0032). The cumulative rate of repeat revascularization at 10 years in patients having low, intermediate and high SYNTAX score were, respectively, 4.6, 15.7 and 16.8%. The cumulative rates of the combined outcomes of death/stroke/MI at 10 years did not show statistical differences between the three groups (22.3% with low, 25.0% with intermediate and 38.4% with high score, log-rank P = 0.063). In the multivariable analysis, the SYNTAX score [hazard ratio (HR) 1.03, P = 0.0043] and logistic EuroSCORE II (HR 1.34, P = 0.0012) were found to be significant predictors of long-term MACCEs.
conclusionsThe SYNTAX score is correlated with long-term outcomes, in terms of MACCEs, after conventional CABG for complex coronary lesions and is prognostic of long-term outcomes of CABG for patients with complex lesions.
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