SynthesisInteractive cardiovascular and thoracic surgery2016
Non-intubated video-assisted thoracoscopic surgery under loco-regional anaesthesia for thoracic surgery: a meta-analysis.
Synthesis in Interactive cardiovascular and thoracic surgery, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05077111 (A Comparative Study Between Thoracic Epidural Anesthesia in Non-Intubated Video-Assisted Thoracoscopes and the Conventional General Anesthesia With One Lung Ventilation), which is not on this map. Cited by 34 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
A Comparative Study Between Thoracic Epidural Anesthesia in Non-Intubated Video-Assisted Thoracoscopes and the Conventional General Anesthesia With One Lung Ventilation
Who cites it
34 citing papers in PubMed, 4 syntheses or guidelines pooled it, 56 citations in OpenAlex.
- Non-intubated vs. intubated video-assisted thoracoscopic surgery for the treatment of thoracic diseases: a systematic review and meta-analysis of propensity score-matched cohorts.Frontiers in surgery · 2025Pooled it
- Pooled it
- Video-Assisted Thoracoscopic Sleeve Lobectomy for Centrally Located Non-small Cell Lung Cancer: A Meta-analysis.World journal of surgery · 2021Pooled it
- Pooled it
- Comparison of postoperative pulmonary complications and intraoperative safety in thoracoscopic surgery under non-intubated versus intubated anesthesia: a randomized, controlled, double-blind non-inferiority trial.Updates in surgery · 2024Trial
- Bibliometric and visualization analysis of non-intubated thoracic anaesthesia [2014-2025].Journal of thoracic disease · 2026Article
- Comparative analysis of safety and efficacy of non-intubation in lung wedge resection using thoracoscopy: a systematic review and meta-analysis.Journal of thoracic disease · 2026Article
- To Breathe or Not to Breathe: Spontaneous Ventilation During Thoracic Surgery in High-Risk COPD Patients-A Feasibility Study.Journal of clinical medicine · 2025Article
- Exploring Benefits of Non-Intubated Surgery for Lung Biopsy in Interstitial Lung Disease.Respirology (Carlton, Vic.) · 2025Article
- Prospective in-depth analysis of anaesthetic management of spontaneous ventilation VATS for lung cancer resection: a matched pairs comparison to intubated VATS.BMC anesthesiology · 2025Article
- Awake versus intubated video-assisted thoracoscopic surgery for pleural disease: a retrospective cohort study from a single tertiary center.Frontiers in surgery · 2025Article
- Advances in the use of non-intubated spontaneous-ventilation video-assisted thoracoscopic surgery.Frontiers in surgery · 2025Review
- Perioperative morbidity and 3-year survival in non-intubated thoracoscopic surgery: a propensity matched analysis.Journal of thoracic disease · 2024Article
- Postoperative pulmonary complications in awake video-assisted thoracoscopic surgery: Our 10-year experience.Turk gogus kalp damar cerrahisi dergisi · 2024Article
- Erector spine plane block as single loco-regional anesthesia in non-intubated video-assisted thoracic surgery for unfit patients: a case-match study.Updates in surgery · 2023Article
- Non-intubated uniportal video-assisted thoracoscopic lobectomy: expanding the boundaries of minimally invasive surgery while mindful of patient safety.Journal of thoracic disease · 2023Article
- Perioperative Systemic Inflammation in Lung Cancer Surgery.Frontiers in surgery · 2022Review
- The Anesthesiologist's Perspective Regarding Non-intubated Thoracic Surgery: A Scoping Review.Frontiers in surgery · 2022Article
- Non-Intubated Thoracic Surgery: Standpoints and Perspectives.Frontiers in surgery · 2022Article
- A risk score for predicting postoperative complications in non-intubated thoracic surgery.Journal of thoracic disease · 2021Article
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesThe short-term feasibility and safety of non-intubated video-assisted thoracoscopic surgery under loco-regional anaesthesia for thoracic surgery remains unknown. Therefore, we conducted a meta-analysis to provide evidence for the short-term efficacy and safety profile of non-intubated video-assisted thoracoscopic surgery under loco-regional anaesthesia for thoracic surgery.
methodsWe performed a systematic literature search in PubMed, Embase, Cochrane Library databases and Google Scholar, as well as American Society of Clinical Oncology to identify relevant studies comparing non-intubated video-assisted thoracoscopic surgery under loco-regional anaesthesia with conventionally intubated video-assisted thoracoscopic surgery under general anaesthesia, dated up to 31 August 2015. Data concerning global in-operating room time, hospital stays, rate of postoperative complications and perioperative mortality were extracted and analysed. We conducted a meta-analysis of the overall results and two subgroup analyses based on study design (a meta-analysis of randomized controlled trials and a second meta-analysis of observational studies).
resultsFour randomized controlled trials and six observational studies with a total of 1283 patients were included. We found that in the overall analysis, patients treated with non-intubated video-assisted thoracoscopic surgery under loco-regional anaesthesia achieved significantly shorter global in-operating room time [weighted mean difference = -41.96; 95% confidence interval (CI) = (-57.26, -26.67); P < 0.001] and hospital stays [weighted mean difference = -1.24; 95% CI = (-1.46, -1.02); P < 0.001] as well as a lower rate of postoperative complications [relative risk = 0.55; 95% CI = (0.40, 0.74); P < 0.001] than patients treated with intubated video-assisted thoracoscopic surgery under general anaesthesia. Subgroup meta-analyses based on study design achieved the same outcomes as overall analysis. In our meta-analysis, no perioperative mortality was observed in patients treated with non-intubated video-assisted thoracoscopic surgery under loco-regional anaesthesia.
conclusionsNon-intubated video-assisted thoracoscopic surgery under loco-regional anaesthesia for thoracic surgery proved to be feasible and safe. Future multicentre and well-designed randomized controlled trials with longer follow-up are needed to confirm and update the findings of our study, as well as the long-term efficacy of non-intubated video-assisted thoracoscopic surgery under loco-regional anaesthesia.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.