ArticleGenetics2016
A Pathway Analysis of Melanin Patterning in a Hemimetabolous Insect.
Article in Genetics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed, 62 citations in OpenAlex.
- Gene Expression and Structural Differences Underpinning Black and White Colouration in Spiders.Molecular ecology · 2026Article
- Disruption of yellow-e3 impairs both adult molting and cuticular melanization in the honeybee (Apis mellifera).Frontiers in zoology · 2026Article
- Evaluation of ebony as a potential selectable marker for genetic sexing in Aedes aegypti.Parasites & vectors · 2025Article
- Structural and Evolutionary Relationships of Melanin Cascade Proteins in Cnidarian Innate Immunity.Integrative and comparative biology · 2024Article
- Polycomb group proteins confer robustness to aposematic coloration in the milkweed bug,Proceedings. Biological sciences · 2024Article
- Long-wave opsin involved in body color plastic development in Nilaparvata lugens.BMC genomics · 2023Article
- Genome editing of the vermilion locus generates a visible eye color marker for Oncopeltus fasciatus.Scientific reports · 2023Article
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- Atypical strategies for cuticle pigmentation in the blood-feeding hemipteran Rhodnius prolixus.Genetics · 2022Article
- The peroxins BcPex8, BcPex10, and BcPex12 are required for the development and pathogenicity ofFrontiers in microbiology · 2022Article
- Silencing ofFrontiers in physiology · 2022Article
- Establishing RNAi for basic research and pest control and identification of the most efficient target genes for pest control: a brief guide.Frontiers in zoology · 2021Review
- Developmental Transcriptomics Reveals a Gene Network Driving Mimetic Color Variation in a Bumble Bee.Genome biology and evolution · 2021Article
- The effect of theBiology letters · 2021Article
- Comparative transcriptomics of albino and warningly-coloured caterpillars.Ecology and evolution · 2021Article
- Yellow-y Functions in Egg Melanization and Chorion Morphology of the Asian Tiger Mosquito,Frontiers in cell and developmental biology · 2021Article
- Article
- Three Melanin Pathway Genes,International journal of molecular sciences · 2019Article
- Molecular evolutionary trends and feeding ecology diversification in the Hemiptera, anchored by the milkweed bug genome.Genome biology · 2019Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
Diversity in insect pigmentation, encompassing a wide range of colors and spatial patterns, is among the most noticeable features distinguishing species, individuals, and body regions within individuals. In holometabolous species, a significant portion of such diversity can be attributed to the melanin synthesis genes, but this has not been formally assessed in more basal insect lineages. Here we provide a comprehensive analysis of how a set of melanin genes (ebony, black, aaNAT, yellow, and tan) contributes to the pigmentation pattern in a hemipteran, Oncopeltus fasciatus For all five genes, RNA interference depletion caused alteration of black patterning in a region-specific fashion. Furthermore, the presence of distinct nonblack regions in forewings and hindwings coincides with the expression of ebony and aaNAT in these appendages. These findings suggest that the region-specific phenotypes arise from regional employment of various combinations of the melanin genes. Based on this insight, we suggest that melanin genes are used in two distinct ways: a "painting" mode, using predominantly melanin-promoting factors in areas that generally lack black coloration, and, alternatively, an "erasing" mode, using mainly melanin-suppressing factors in regions where black is the dominant pigment. Different combinations of these strategies may account for the vast diversity of melanin patterns observed in insects.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.