ArticlePlant physiology2016
A Cation-Chloride Cotransporter Gene Is Required for Cell Elongation and Osmoregulation in Rice.
Article in Plant physiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
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Who cites it
29 citing papers in PubMed.
- Chloride-Transporting OsHKT1;1 Splice Variants and Their Expression Profiles Under Salinity Stress in Rice.International journal of molecular sciences · 2026Article
- OsCAX1a-Dependent Ca-Mg Balance Is Required for Optimal Growth in Rice.Rice (New York, N.Y.) · 2025Article
- Loci and natural alleles for leaf length and width revealed by a genome wide association study in adzuki bean.BMC plant biology · 2025Article
- Rhizosphere microorganisms mediate ion homeostasis in cucumber seedlings: a new strategy to improve plant salt tolerance.BMC plant biology · 2025Article
- Chloride transport and homeostasis in plants.Quantitative plant biology · 2025Review
- Protein Structural Modeling and Transport Thermodynamics Reveal That Plant Cation-Chloride Cotransporters Mediate Potassium-Chloride Symport.International journal of molecular sciences · 2024Article
- Natural variation in the Tn1a promoter regulates tillering in rice.Plant biotechnology journal · 2024Article
- Genome-wide association study and genomic selection of spike-related traits in bread wheat.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2024Article
- Advancements in Rice Leaf Development Research.Plants (Basel, Switzerland) · 2024Review
- Plant Growth Regulation in Cell and Tissue Culture In Vitro.Plants (Basel, Switzerland) · 2024Review
- Ion Changes and Signaling under Salt Stress in Wheat and Other Important Crops.Plants (Basel, Switzerland) · 2023Review
- Identification of a Rice Leaf Width GeneInternational journal of molecular sciences · 2023Article
- Article
- New insights into light spectral quality inhibits the plasticity elongation of maize mesocotyl and coleoptile during seed germination.Frontiers in plant science · 2023Article
- Genome-wide association study reveals a genomic region on 5AL for salinity tolerance in wheat.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2022Article
- Plant Trans-Golgi Network/Early Endosome pH regulation requires Cation Chloride Cotransporter (CCC1).eLife · 2022Article
- Genome Editing Targets for Improving Nutrient Use Efficiency and Nutrient Stress Adaptation.Frontiers in genetics · 2022Review
- Genetic dissection of heterosis of indica-japonica by introgression line, recombinant inbred line and their testcross populations.Scientific reports · 2021Article
- Genome-Wide Association Study Identified Novel Candidate Loci/Genes Affecting Lodging Resistance in Rice.Genes · 2021Article
- Tissue-specific expression analysis of NaBMC plant biology · 2020Article
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4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Rice (Oryza sativa) is characterized by having fibrous root systems; however, the molecular mechanisms underlying the root development are not fully understood. Here, we isolated a rice mutant with short roots and found that the mutant had a decreased cell size of the roots and shoots compared with wild-type rice. Map-based cloning combined with whole-genome sequencing revealed that a single nucleotide mutation occurred in a gene, which encodes a putative cation-chloride cotransporter (OsCCC1). Introduction of OsCCC1 cDNA into the mutant rescued the mutant growth, indicating that growth defects of both the roots and shoots are caused by loss of function of OsCCC1. Physiological analysis showed that the mutant had a lower concentration of Cl(-) and K(+) and lower osmolality in the root cell sap than the wild type at all KCl supply conditions tested; however, the mutant only showed a lower Na(+) concentration at high external Na(+) Expression of OsCCC1 in yeast increased accumulation of K(+), Na(+), and Cl(-) The expression of OsCCC1 was found in both the roots and shoots, although higher expression was found in the root tips. Furthermore, the expression in the roots did not respond to different Na(+), K(+), and Cl(-) supply. OsCCC1 was expressed in all cells of the roots, leaf, and basal node. Immunoblot analysis revealed that OsCCC1 was mainly localized to the plasma membrane. These results suggest that OsCCC1 is involved in the cell elongation by regulating ion (Cl(-), K(+), and Na(+)) homeostasis to maintain cellular osmotic potential.
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