Evidence map›Paper›PMID 26983442›Full record

ArticleBMC research notes2016

Vulvar intraepithelial neoplasia grade 3 associated with Behçet's disease.

Daphné Germann, Rosa Catarino, Essia Saiji, Thomas Daikeler, Patrick Petignat, Pierre Vassilakos

Open access · goldAbstract readCase Reports
In one paragraph

Article in BMC research notes, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.3field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Daphné GermannDepartment of Gynecology and Obstetrics, Geneva University Hospitals, Geneva, Switzerland. daphne.germann@gmail.com.ORCID http://orcid.org/0000-0003-2159-367X
Rosa CatarinoDepartment of Gynecology and Obstetrics, Geneva University Hospitals, Geneva, Switzerland.
Essia SaijiDepartment of Pathology, Geneva University Hospitals, Geneva, Switzerland.
Thomas DaikelerDepartment of Rheumatology, Basel University Hospitals, Basel, Switzerland.
Patrick PetignatDepartment of Gynecology and Obstetrics, Geneva University Hospitals, Geneva, Switzerland.
Pierre VassilakosGeneva Foundation for Medical Education and Research, Geneva, Switzerland.
University Hospital of Geneva · CHFoundation for laboratory medicine · CHUniversity Hospital of Basel · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLittle information is available regarding the association between vulvar intraepithelial neoplasia grade 3 (VIN3) and Behçet's disease (BD). We report here concomitant VIN3 and genital ulcers in a patient with BD. CASE: A 44-year-old Caucasian woman with a history of BD, which had been evolving for 6 years, presented with ulcerated and papillomatous lesions on the vulva. Biopsies revealed a multifocal VIN3 positive for high-risk human papillomavirus (HPV) 33. Multiple biopsies were performed to exclude invasive cancer and VIN3 was treated with laser vaporization.

conclusionWe report clinical and anatomopathological features of a rare case of multifocal, high-risk, HPV-related VIN3. We also discuss the possible pathogenesis in the context of BD, featuring chronic ulceration and intrinsic or treatment-induced immunosuppression.

Indexed as

AdultBehcet SyndromeCarcinoma in SituFemaleHumansNeoplasm GradingVulvar NeoplasmsBehçet’s diseaseGenital ulcerationHuman papillomavirusVulvar intraepithelial neoplasia

Identifiers

PMID26983442
PMCPMC4794835
OpenAlexW2298640384

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.