Evidence map›Paper›PMID 26983432›Full record

ArticleSurgical endoscopy2016

The effect of intermittent intraabdominal pressure elevations and low cardiac output on the femoral to carotid arterial blood pressure difference in piglets.

Devrim Aksakal, Thomas Hückstädt, Steffen Richter, Daniela Klitscher, Tobias Wowra, Felix Schier, Lucas M Wessel, Rainer Kubiak

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Article in Surgical endoscopy, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Devrim AksakalDepartment of Pediatric Surgery, Medical Faculty Mannheim (UMM), University of Heidelberg, Theodor-Kutzer-Ufer 1-3, 68167, Mannheim, Germany.
Thomas HückstädtDepartment of Pediatric Surgery, University Medical Center, Langenbeckstrasse 1, 55101, Mainz, Germany.
Steffen RichterDepartment of Pediatric Surgery, University Medical Center, Langenbeckstrasse 1, 55101, Mainz, Germany.
Daniela KlitscherDepartment of Traumatology, University Medical Center, Langenbeckstrasse 1, 55101, Mainz, Germany.
Tobias WowraDepartment of Pediatric Surgery, University Medical Center, Langenbeckstrasse 1, 55101, Mainz, Germany.
Felix SchierDepartment of Pediatric Surgery, University Medical Center, Langenbeckstrasse 1, 55101, Mainz, Germany.
Lucas M WesselDepartment of Pediatric Surgery, Medical Faculty Mannheim (UMM), University of Heidelberg, Theodor-Kutzer-Ufer 1-3, 68167, Mannheim, Germany.
Rainer KubiakDepartment of Pediatric Surgery, Medical Faculty Mannheim (UMM), University of Heidelberg, Theodor-Kutzer-Ufer 1-3, 68167, Mannheim, Germany. rainerkubiak@hotmail.com.
Johannes Gutenberg University Mainz · DEHeidelberg University · DEUniversity Hospital Heidelberg · DEUniversity Medical Centre Mannheim · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundOur previous work in a laparoscopic setting in piglets revealed that the systolic femoral artery pressure was approximately 5 % higher than its carotid counterpart, whereas the mean and diastolic values showed no significant difference. This remained idem when the intraabdominal pressure (IAP) was gradually increased. In this study, we aimed to investigate the effect of (1) intermittent IAP elevations and (2) a low cardiac output (CO) on the blood pressure (BP) difference cranially (carotid artery) and caudally (femoral artery) of a capnoperitoneum (ΔP = P

methodsA total of twenty-two piglets (mean body weight 11.0 kg; range 8.9-13.3 kg) were studied. Of these, 14 underwent intermittent IAP elevations at 8 and 16 mmHg, and ΔP was measured. In another 8 piglets, a model of reduced CO was created by introducing an air embolism (2 ml/kg over 30 s) in the inferior caval vein (VCI) at 12 mmHg IAP to further assess the influence of this variable on ΔP.

resultsSystolic ΔP remained at a mean of 5.6 mmHg and was not significantly affected by insufflation or exsufflation up to an IAP of 16 mmHg. Diastolic and mean values showed no differences between P

conclusionsIntermittent IAP elevations do not significantly influence ΔP. Despite of a CO-dependent inversion of systolic ΔP, mean BP measurements at the leg during laparoscopy remain representative even at low CO values.

Indexed as

AnimalsArterial PressureBlood PressureCardiac Output, LowCarotid ArteriesFemoral ArteryInsufflationLaparoscopyModels, AnimalPneumoperitoneum, ArtificialPressureSwineArterial blood pressure differenceCapnoperitoneumCardiac outputLaparoscopyPiglets

Identifiers

PMID26983432
OpenAlexW2300364682

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.