Evidence map›Paper›PMID 26983372›Full record

ArticleScientific reports2016

Acute Kidney Injury Classification for Critically Ill Cirrhotic Patients: A Comparison of the KDIGO, AKIN, and RIFLE Classifications.

Heng-Chih Pan, Yu-Shan Chien, Chang-Chyi Jenq, Ming-Hung Tsai, Pei-Chun Fan, Chih-Hsiang Chang, Ming-Yang Chang, Ya-Chung Tian, Ji-Tseng Fang, Chih-Wei Yang and 1 more

Abstract read
In one paragraph

Article in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 3 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Heng-Chih PanKidney Research Center, Department of Nephrology, Chang Gung Memorial Hospital, Taipei, Taiwan.
Yu-Shan ChienDepartment of Internal Medicine, Chang Gung Memorial Hospital, Taipei, Taiwan.
Chang-Chyi JenqKidney Research Center, Department of Nephrology, Chang Gung Memorial Hospital, Taipei, Taiwan.
Ming-Hung TsaiDivision of Gastroenterology, Chang Gung Memorial Hospital, Taipei, Taiwan.
Pei-Chun FanKidney Research Center, Department of Nephrology, Chang Gung Memorial Hospital, Taipei, Taiwan.
Chih-Hsiang ChangKidney Research Center, Department of Nephrology, Chang Gung Memorial Hospital, Taipei, Taiwan.
Ming-Yang ChangKidney Research Center, Department of Nephrology, Chang Gung Memorial Hospital, Taipei, Taiwan.
Ya-Chung TianKidney Research Center, Department of Nephrology, Chang Gung Memorial Hospital, Taipei, Taiwan.
Ji-Tseng FangKidney Research Center, Department of Nephrology, Chang Gung Memorial Hospital, Taipei, Taiwan.
Chih-Wei YangKidney Research Center, Department of Nephrology, Chang Gung Memorial Hospital, Taipei, Taiwan.
Yung-Chang ChenKidney Research Center, Department of Nephrology, Chang Gung Memorial Hospital, Taipei, Taiwan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Critically ill cirrhotic patients have high mortality rates, particularly when they present with acute kidney injury (AKI) on admission. The Kidney Disease: Improving Global Outcomes (KDIGO) group aimed to standardize the definition of AKI and recently published a new AKI classification. However, the efficacy of the KDIGO classification for predicting outcomes of critically ill cirrhotic patients is unclear. We prospectively enrolled 242 cirrhotic patients from a 10-bed specialized hepatogastroenterology intensive care unit (ICU) in a 2000-bed tertiary-care referral hospital. Demographic parameters and clinical variables on day 1 of admission were prospectively recorded. The overall in-hospital mortality rate was 62.8%. Liver diseases were usually attributed to hepatitis B viral infection (26.9%). The major cause of ICU admission was upper gastrointestinal bleeding (38.0%). Our result showed that the KDIGO classification had better discriminatory power than RIFLE and AKIN criteria in predicting in-hospital mortality. Cumulative survival rates at the 6-month after hospital discharge differed significantly between patients with and without AKI on ICU admission day. In summary, we identified that the outcome prediction performance of KDIGO classification is superior to that of AKIN or RIFLE classification in critically ill cirrhotic patients.

Indexed as

Acute Kidney InjuryAdultAgedCritical IllnessFemaleGastrointestinal HemorrhageHepatitis BHospital MortalityHumansKaplan-Meier EstimateKidney Failure, ChronicLiver CirrhosisMaleMiddle AgedOdds RatioPrognosis

Identifiers

PMID26983372
PMCPMC4794801

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.