ArticleEmerging infectious diseases2016
Microevolution of Monophasic Salmonella Typhimurium during Epidemic, United Kingdom, 2005-2010.
Article in Emerging infectious diseases, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 111 papers.
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Who cites it
111 citing papers in PubMed.
- Global transmission dynamics of antibiotic resistance genes: Foodborne pathways as the critical link to humans.One health (Amsterdam, Netherlands) · 2026Article
- Comparative genomics of the monophasic variant ofMicrobiology spectrum · 2026Article
- Sequential gene loss promotes expansion of monophasic Salmonella Typhimurium ST34.Nature microbiology · 2026Article
- Outbreak of multidrug-resistant Salmonella typhimurium monophasic variant 1,4,[5],12:i:- sequence type 34 linked to food, in China.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2026Article
- Copper is an intestinal habitat filter affecting the gut microbiota interactions with Salmonella Typhimurium.Microbiome · 2026Article
- Transmission of Salmonella clones between different animal species in a horse and cattle breeding region in Japan.Scientific reports · 2026Article
- Epidemiology, antimicrobial resistance transmission, and One Health-based prevention of non-typhoidalFrontiers in microbiology · 2026Review
- Emergence ofFrontiers in microbiology · 2026Article
- Prophage diversity in poultry-associatedFrontiers in microbiology · 2026Article
- Localization of the origin of transfer for Salmonella genomic island 4 from Salmonella enterica serovar I 4,[5],12:i:.DNA research : an international journal for rapid publication of reports on genes and genomes · 2025Article
- Article
- Evolutionary adaptations of a pediatric pathogen: low-inflammatory and high-resistance phenotypes in the emergingMicrobiology spectrum · 2025Article
- Identification of multidrug-resistant monophasic Salmonella Typhimurium ST34 and other NTS from animal-environmental origins in South Africa.npj antimicrobials and resistance · 2025Article
- Unveiling the Genetic Diversity and Antimicrobial Resistance Profiles of Salmonella Population From 2016 to 2020 in Thai Canal Water.Environmental microbiology reports · 2025Article
- Prevalence ofChina CDC weekly · 2025Article
- Reversible excision of the wzy locus in Salmonella Typhimurium may aid recovery following phage predation.PLoS genetics · 2025Article
- Using GWAS and Machine Learning to Identify and Predict Genetic Variants Associated with Foodborne Bacteria Phenotypic Traits.Methods in molecular biology (Clifton, N.J.) · 2025Review
- Exploring the genetic landscape of the Copper Homeostasis and Silver Resistance Island (CHASRI) in Salmonella enterica.PloS one · 2025Article
- Genomic characteristics and antibiotic resistance profiles of monophasicFrontiers in microbiology · 2025Article
- Potential links between human bloodstream infection by Salmonella enterica serovar Typhimurium and international transmission to Colombia.PLoS neglected tropical diseases · 2025Article
51 more citing papers are in PubMed but not listed here.
Corrections and comments
- Erratum issued
Authors and funding
16 authors.
Funding
Abstract
Microevolution associated with emergence and expansion of new epidemic clones of bacterial pathogens holds the key to epidemiologic success. To determine microevolution associated with monophasic Salmonella Typhimurium during an epidemic, we performed comparative whole-genome sequencing and phylogenomic analysis of isolates from the United Kingdom and Italy during 2005-2012. These isolates formed a single clade distinct from recent monophasic epidemic clones previously described from North America and Spain. The UK monophasic epidemic clones showed a novel genomic island encoding resistance to heavy metals and a composite transposon encoding antimicrobial drug resistance genes not present in other Salmonella Typhimurium isolates, which may have contributed to epidemiologic success. A remarkable amount of genotypic variation accumulated during clonal expansion that occurred during the epidemic, including multiple independent acquisitions of a novel prophage carrying the sopE gene and multiple deletion events affecting the phase II flagellin locus. This high level of microevolution may affect antigenicity, pathogenicity, and transmission.
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