ArticlePloS one2016
Set Configuration in Resistance Exercise: Muscle Fatigue and Cardiovascular Effects.
Article in PloS one, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
12 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- The specificity of cluster training effects in sports: a systematic review and meta-analysis.Frontiers in physiology · 2025Pooled it
- The Acute Neuromuscular Responses to Cluster Set Resistance Training: A Systematic Review and Meta-Analysis.Sports medicine (Auckland, N.Z.) · 2019Pooled it
- Shorter Set Configurations Attenuate Performance Loss and Lactatemia During Resistance Training in Postmenopausal Women: A Randomized Crossover Trial (CARE Project).Journal of strength and conditioning research · 2026Trial
- Set configuration influences cardiovascular responses to resistance exercise in postmenopausal females in a randomized crossover trial from the CARE project.Scientific reports · 2025Trial
- Acute Effects of a Percussive Massage Treatment on Movement Velocity during Resistance Training.International journal of environmental research and public health · 2021Trial
- Study on the differences in peripheral fatigue responses elicitation effects of bench press training with different loads and tempos based on electromyography and motion sensors.Frontiers in physiology · 2025Article
- Article
- Strengthening the Case for Cluster Set Resistance Training in Aged and Clinical Settings: Emerging Evidence, Proposed Benefits and Suggestions.Sports medicine (Auckland, N.Z.) · 2021Article
- Impact of Rest-Redistribution on Fatigue During Maximal Eccentric Knee Extensions.Journal of human kinetics · 2020Article
- CHANGES IN INFRASPINATUS AND LOWER TRAPEZIUS ACTIVATION IN VOLLEYBALL PLAYERS FOLLOWING REPETITIVE SERVES.International journal of sports physical therapy · 2020Article
- Blood Pressure Increase in Hypertensive Individuals During Resistance Training Protocols With Equated Work to Rest Ratio.Frontiers in physiology · 2020Article
- Three different motor task strategies to assess neuromuscular adjustments during fatiguing muscle contractions in young and older men.Experimental brain research · 2018Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeCardiovascular responses of traditional resistance (TS) training have been extensively explored. However, the fatigue mechanisms associated with an intra-set rest configuration (ISR) have not been investigated. This study compares two modalities of set configurations for resistance exercise that equates work to rest ratios and measures the central and peripheral fatigue in combination with cortical, hemodynamic and cardiovascular measures.
methods11 subjects performed two isometric knee extension training sessions using TS and ISR configurations. Voluntary activation (VA), single twitch amplitude, low frequency fatigue (LFF), Mwave, motor evoked potential (MEP), short intracortical inhibition (SICI), intracortical facilitation (ICF) and heart rate variability were evaluated before and after each training session. During each session beat to beat heart rate, blood pressure and rate pressure product (RPP) were also evaluated.
resultsAfter exercise VA decreased significantly for TS but not for ISR (P < 0.001), single twitch amplitude and LFF values were lower for TS than ISR (P < 0.004), and SICI was reduced only for the TS configuration (P = 0.049). During exercise RPP values were significantly higher for the TS than for ISR (P = 0.001). RPP correlated with VA for TS (r = -.85 P < 0.001) suggesting a relationship between central fatigue and cardiovascular stress.
conclusionsWe conclude that ISR induced lower central and peripheral fatigue as well as lower cardiovascular stress in comparison with TS configuration. Our study suggests that set configuration is a key factor in the regulation of the neuromuscular and cardiovascular responses of resistance training.
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