Evidence map›Paper›PMID 26981444›Full record

ReviewWorld journal of nephrology2016

Experimental models of renal calcium stones in rodents.

Héloïse Bilbault, Jean-Philippe Haymann

Open access · hybridAbstract readReview
In one paragraph

Review in World journal of nephrology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 27 citations in OpenAlex.

  1. The effect ofNorthern clinics of Istanbul · 2024
    Article
  2. Article
  3. Article
  4. Kidney stone formation in a novel murine model of polycystic kidney disease.American journal of physiology. Renal physiology · 2022
    Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Progress in Understanding the Genetics of Calcium-Containing Nephrolithiasis.Journal of the American Society of Nephrology : JASN · 2017
    Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 2 countries.

Héloïse BilbaultHéloïse Bilbault, Jean-Philippe Haymann, Institut National de la Santé et de la Recherche Médicale, UMR_S 1155, 75020 Paris, France.
Jean-Philippe HaymannHéloïse Bilbault, Jean-Philippe Haymann, Institut National de la Santé et de la Recherche Médicale, UMR_S 1155, 75020 Paris, France.
Creative Research Enterprises (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In human nephrolithiasis, most stones are containing calcium and are located within urinary cavities; they may contain monohydrate calcium oxalate, dihydrate calcium oxalate and/or calcium phosphates in various proportion. Nephrolithiasis may also be associated with nephrocalcinosis, i.e., crystal depositions in tubular lumen and/or interstitium, an entity which suggests specific pathological processes. Several rodents models have been developed in order to study the pathophysiology of intrarenal crystal formation. We review here calcium rodent models classified upon the presence of nephrolithiasis and/or nephrocalcinosis. As rodents are not prone to nephrolithiasis, models require the induction of a long standing hypercalciuria or hyperoxaluria (thus explaining the very few studies reported), conversely to nephrocalcinosis which may occur within hours or days. Whereas a nephrotoxicity leading to tubular injury and regeneration appears as a critical event for crystal retention in nephrocalcinosis models, surprisingly very little is known about the physiopathology of crystal attachment to urothelium in nephrolithiasis. Creating new models of nephrolithiasis especially in different genetic mice strains appears an important challenge in order to unravel the early mechanisms of urinary stone formation in papilla and fornices.

Indexed as

CrystalNephrocalcinosisNephrolithiasisOxalateUrothelium

Identifiers

PMID26981444
PMCPMC4777791
OpenAlexW2334040449

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.