ReviewWorld journal of nephrology2016
Upper tract urothelial carcinoma: Paradigm shift towards nephron sparing management.
Review in World journal of nephrology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
27 citing papers in PubMed.
- Performance of Urine Fluorescence In Situ Hybridization for Diagnosis of Upper Tract Urothelial Carcinoma: A Comprehensive Review.International journal of molecular sciences · 2026Review
- Radiosurgery in Upper Tract Urothelial Carcinoma (UTUC).Cancers · 2026Article
- Review
- Kidney Stone History and Survival Outcomes in Upper Tract Urothelial Carcinoma.JAMA network open · 2025Article
- The Recurrence Rates at Three Years for the Conservatively Managed UTUC Cases Using NBI-Assisted Flexible Ureteroscopy and Holmium Laser Vaporization.Medicina (Kaunas, Lithuania) · 2024Article
- Kidney-Sparing Surgery for Upper Tract Urothelial Carcinoma-Modalities, Outcomes, and Limitations.Journal of clinical medicine · 2024Review
- Overview, Diagnosis, and Perioperative Systemic Therapy of Upper Tract Urothelial Carcinoma.Cancers · 2023Review
- Robotic-assisted versus laparoscopic nephroureterectomy; a systematic review and meta-analysis.BJUI compass · 2023Review
- Promising Response of Paclitaxel in Metastatic Transitional Cell Carcinoma of Distal Ureter Complicated with Hydroureteronephrosis: A Case Report.JNMA; journal of the Nepal Medical Association · 2023Article
- First experience in treating advanced urothelial cancer with enfortumab vedotin. Single-centre retrospective study of patients qualified for a rescue access procedure.Contemporary oncology (Poznan, Poland) · 2023Article
- Successful Kidney-Sparing Systemic Therapy for a High-Risk Ureteral Carcinoma Case.Urologia internationalis · 2023Article
- Treatment Patterns, Outcomes, and Costs Associated With Localized Upper Tract Urothelial Carcinoma.JNCI cancer spectrum · 2021Article
- Conservative Treatment of Upper Urinary Tract Urothelial Carcinoma: Referee.European urology open science · 2021Article
- Nephron-sparing management of upper tract urothelial carcinoma.Investigative and clinical urology · 2021Review
- Article
- Prognostic impact of perirenal fat stranding on oncologic outcomes in ureteral urothelial carcinoma.Investigative and clinical urology · 2021Article
- Nephron-sparing surgery for the management of upper tract urothelial carcinoma: an outline of surgical technique and review of outcomes.Translational andrology and urology · 2020Review
- CT-based radiomics to predict the pathological grade of bladder cancer.European radiology · 2020Article
- Nephron-sparing approaches in the management of upper tract urothelial carcinoma: indications and clinical outcomes.Translational cancer research · 2020Review
- Controversies in management of the bladder cuff at nephroureterectomy.Translational andrology and urology · 2020Review
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Upper tract urothelial carcinoma (UTUC) is relatively rare compared to urothelial carcinoma of the lower tract, comprising only 5%-10% of all urothelial cancers. Although both entities share histologic properties, UTUC tends to be more invasive at diagnosis and portend a worse prognosis, with a 5 year overall mortality of 23%. To date, the gold standard management of UTUC has been radical nephroureterectomy (RNU), with nephron sparing techniques reserved for solitary kidneys or cases where the patient could not tolerate radical surgery. Limited data from these series, as well as select series where nephron-sparing endoscopic management has been offered to a broader patient base, suggest that minimally invasive, nephron sparing techniques can offer comparable oncologic and survival outcomes to RNU in appropriately selected patients. We review the current literature on the topic and discuss long term outcomes and sequelae of the gold standard treatment, RNU. We also discuss the oncologic outcomes of minimally invasive, endoscopic management of UTUC. Our goal is to provide the reader a comprehensive overview of the current state of the field in order to inform and guide their treatment decisions.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.