Evidence map›Paper›PMID 26981202›Full record

ReviewWorld journal of biological chemistry2016

Development of regional specificity of spinal and medullary dorsal horn neurons.

Yu-Feng Xie, Xing-Hong Jiang, Barry J Sessle, Xian-Min Yu

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PubMed Full text at PMC Publisher
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Review in World journal of biological chemistry, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Yu-Feng XieYu-Feng Xie, Leslie Dan Faculty of Pharmacy, University of Toronto M5S 3M3, Canada.
Xing-Hong JiangYu-Feng Xie, Leslie Dan Faculty of Pharmacy, University of Toronto M5S 3M3, Canada.
Barry J SessleYu-Feng Xie, Leslie Dan Faculty of Pharmacy, University of Toronto M5S 3M3, Canada.
Xian-Min YuYu-Feng Xie, Leslie Dan Faculty of Pharmacy, University of Toronto M5S 3M3, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Extensive studies have focused on the development and regionalization of neurons in the central nervous system (CNS). Many genes, which play crucial roles in the development of CNS neurons, have been identified. By using the technique "direct reprogramming", neurons can be produced from multiple cell sources such as fibroblasts. However, understanding the region-specific regulation of neurons in the CNS is still one of the biggest challenges in the research field of neuroscience. Neurons located in the trigeminal subnucleus caudalis (Vc) and in the spinal dorsal horn (SDH) play crucial roles in pain and sensorimotor functions in the orofacial and other somatic body regions, respectively. Anatomically, Vc represents the most caudal component of the trigeminal system, and is contiguous with SDH. This review is focused on recent data dealing with the regional specificity involved in the development of neurons in Vc and SDH.

Indexed as

Central nervous systemDevelopmentPainRegionalizationSpinal cordTrigeminal subnucleus caudalis

Identifiers

PMID26981202
PMCPMC4768117

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.