Evidence map›Paper›PMID 26981068›Full record

ArticleNeural regeneration research2016

Magnetic resonance imaging and cell-based neurorestorative therapy after brain injury.

Quan Jiang

Open access · goldAbstract read
In one paragraph

Article in Neural regeneration research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Quan JiangDepartment of Neurology, Henry Ford Hospital, Detroit, MI, USA.ORCID 0000-0001-7908-4443
Henry Ford Hospital · US

Funding

In vivo MR Evaluation of Cell Therapy for StrokeR01NS048349 · NINDS · HENRY FORD HEALTH SYSTEM · PI JIANG, QUAN · 2005 to 2009
$1.6M
Imaging Cell Based Treatment of Traumatic Brain InjuryR01NS064134 · NINDS · HENRY FORD HEALTH SYSTEM · PI JIANG, QUAN · 2011 to 2014
$1.3M
NINDS NIH HHS R01 NS048349NINDS NIH HHS R01 NS064134
6 · The paper itself

Abstract

Restorative cell-based therapies for experimental brain injury, such as stroke and traumatic brain injury, substantially improve functional outcome. We discuss and review state of the art magnetic resonance imaging methodologies and their applications related to cell-based treatment after brain injury. We focus on the potential of magnetic resonance imaging technique and its associated challenges to obtain useful new information related to cell migration, distribution, and quantitation, as well as vascular and neuronal remodeling in response to cell-based therapy after brain injury. The noninvasive nature of imaging might more readily help with translation of cell-based therapy from the laboratory to the clinic.

Indexed as

angiogenesisaxonal remodelingblood brain barrier permeabilitycell labelingcell therapycerebral blood flowcerebral blood volumediffusion tensor MRIMRIneuronal plasticitystroketraumatic brain injuryvascular remodeling

Identifiers

PMID26981068
PMCPMC4774231
OpenAlexW2284892507

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.