ArticleSaudi journal of biological sciences2016
Antioxidant, α-glucosidase inhibitory and anti-inflammatory effects of aerial parts extract from Korean crowberry (Empetrum nigrum var. japonicum).
Article in Saudi journal of biological sciences, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed.
- Comparative LC-MS Analysis and In Vitro Evaluation of Antioxidant, Antimicrobial, and Enzyme Inhibitory Properties of Ultrasound-Assisted and Soxhlet Extracts of Cachrys cristata DC.Chemistry & biodiversity · 2026Article
- Natural Antidiabetic Agents: Insights into Ericaceae-Derived Phenolics and Their Role in Metabolic and Oxidative Modulation in Diabetes.Pharmaceuticals (Basel, Switzerland) · 2025Review
- A comprehensive review on anti-inflammatory plants: a mechanistic insight through preclinical and clinical studies.Inflammopharmacology · 2025Review
- Antioxidant and Antifungal Activities and Characterization of Phenolic Compounds Using High-Performance Liquid Chromatography and Mass Spectrometry (HPLC-MS) inPlants (Basel, Switzerland) · 2024Article
- Article
- Presence of pyrroloquinazoline alkaloid inBioImpacts : BI · 2021Article
- Antidiabetic activities of Bolanthus spergulifolius (Caryophyllaceae) extracts on insulin-resistant 3T3-L1 adipocytes.PloS one · 2021Article
- Article
- Phenolic Profile, Antioxidant, and Antidiabetic Potential Exerted by Millet Grain Varieties.Antioxidants (Basel, Switzerland) · 2020Article
- Investigation of the Antioxidant, α-Glucosidase Inhibitory, Anti-inflammatory, and DNA Protective Properties ofTurkish journal of pharmaceutical sciences · 2019Article
- Evaluation of Antioxidant, Antidiabetic and Antiobesity Potential of Selected Traditional Medicinal Plants.Frontiers in nutrition · 2019Article
- Evaluation of anti-nociceptive, anti-inflammatory and antipyretic potential ofSaudi journal of biological sciences · 2018Article
- A probe into effect of Shoutai pill on endometrial receptivity.Experimental and therapeutic medicine · 2018Article
- Impact of different partitioned solvents on chemical composition and bioavailability of Sasa quelpaertensis Nakai leaf extract.Journal of food and drug analysis · 2017Article
- Black Crowberry (Empetrum nigrum L.) Flavonoids and Their Health Promoting Activity.Molecules (Basel, Switzerland) · 2016Review
- Antioxidants Content in Empetrum nigrum Fresh and Dried Fruits.Iranian journal of public health · 2016Article
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Authors and funding
4 authors.
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No grant is acknowledged in the PubMed record.
Abstract
Crowberry (Empetrum nigrum L.) is a wild berry commonly found in the northern hemisphere. Crowberry fruits have been suggested as good resources for functional applications in the cosmetic and pharmaceutical industries, but the high polyphenolic content in crowberry leaves also indicates crowberry aerial parts as potential dietary health supplements. In this study, therefore, the biological activities of the aerial parts of Korean crowberry (E. nigrum var. japonicum) were investigated. Antioxidant activity was measured by three different assays on DPPH free radical scavenging, reducing power, and total antioxidant capacities. Dose-dependent antioxidant activities were exhibited by crude methanol extract and its fractions, suggesting that the crude methanol extract and EtOAc fraction possessed strong antioxidant activities and capacities. In addition, the crude methanol extract and EtOAc strongly inhibited α-glucosidase activity and suppressed the secretion of pro-inflammatory mediator and nitrite oxide from LPS-stimulated RAW 264.7 cells. These findings provide valuable evidence for the potential of such parts as good dietary sources of natural antioxidant, α-glucosidase inhibitory, and anti-inflammatory components, suggesting that using the non-edible parts (e.g., leaves and stems) of crowberry can be a potential natural avenue for improving human health.
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