Evidence map›Paper›PMID 26980931›Full record

ArticleMedical archives (Sarajevo, Bosnia and Herzegovina)2016

Elevated Liver Enzymes in Cases of Preeclampsia and Intrauterine Growth Restriction.

Ramadan Dacaj, Sebija Izetbegovic, Goran Stojkanovic, Skender Dreshaj

Open access · greenAbstract readComparative Study
In one paragraph

Article in Medical archives (Sarajevo, Bosnia and Herzegovina), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
2.3field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 54 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Ramadan DacajDepartment of Obstetrics and Gynecology, Regional Hospital, Pec, Republic of Kosova.
Sebija IzetbegovicPrivate Gynecological Surgery, Sarajevo, Bosnia and Herzegovina.
Goran StojkanovicPrivate Gynecological Surgery, Sarajevo, Bosnia and Herzegovina.
Skender DreshajDepartment of Obstetrics and Gynecology, Regional Hospital, Pec, Republic of Kosova.
Academy of Medical Sciences of Bosnia and Herzegovina · BA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimThe aim of this study was to evaluate biochemical parameters in serum of women with preeclampsia and IUGR. MATERIAL AND

methodsA clinical prospective study was conducted and included 120 pregnant women divided in two groups: non IUGR group included healthy pregnant women (n=60) and IUGR group included pregnant women with preeclampsia and IUGR (n=60). Outcome measures were following values of biochemical parameters in serum of mother and fetuses: aspartate aminotransferase (AST), alanine aminotransferase (ALT), lactate dehydrogenase (LDH), bilirubin (indirect and direct) and cholesterol. A blood for analysis was drawn from the cubital vein of mothers and the umbilical vein of the fetuses during delivery period.

resultsThe mean of maternal age was 30.0±6.1 years in women with preeclampsia and IUGR and 28.1±5.1 years in healthy pregnant women, p > 0.05. The most of women with preeclampsia and IUGR had grade III of placental maturation (48.3%). There is a significant association between the placental maturation and the diagnosis, p < 0.001. There was a statistically significant difference in body mass of newborns between IUGR and non IUGR groups, p < 0.001. There was a significant statistically difference in serum value of AST, ALT, LDH and total cholesterol between women with preeclampsia and IUGR and healthy pregnant women (all p < 0.001).

conclusionMeasurement of AST, ALT, LDH, and total cholesterol in serum of pregnant women and newborns with IUGR allows the differentiation and threatening risk of perinatal complications due to hypoxia.

Indexed as

AdultAlanine TransaminaseAspartate AminotransferasesBilirubinBiomarkersBirth WeightBody Mass IndexCholesterolFemaleFetal Growth RetardationHumansInfant, NewbornL-Lactate DehydrogenasePredictive Value of TestsPre-EclampsiaPregnancyAlanine TransaminaseAspartate AminotransferasesBilirubinBiomarkersCholesterolL-Lactate Dehydrogenasebiochemical parametersintrauterine growth restrictionliver of fetusPreeclampsia

Identifiers

PMID26980931
PMCPMC4779350
OpenAlexW2300225655

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.