Evidence map›Paper›PMID 26980817›Full record

ReviewAdvances in nutrition (Bethesda, Md.)2016

Culinary Spice Plants in Dietary Supplement Products and Tested in Clinical Trials.

Leila G Saldanha, Johanna T Dwyer, Joseph M Betz

Open access · bronzeAbstract readReview
In one paragraph

Review in Advances in nutrition (Bethesda, Md.), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.

  1. Pooled it
  2. Chemical Composition of theAntibiotics (Basel, Switzerland) · 2023
    Article
  3. Article
  4. Modernization of the National Institutes of Health Dietary Supplement Label Database.Journal of food composition and analysis : an official publication of the United Nations University, International Network of Food Data Systems · 2021
    Article
  5. Review
  6. Review
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Leila G SaldanhaOffice of Dietary Supplements, National Institutes of Health, Bethesda, MD saldanhl@mail.nih.gov.
Johanna T DwyerOffice of Dietary Supplements, National Institutes of Health, Bethesda, MD.
Joseph M BetzOffice of Dietary Supplements, National Institutes of Health, Bethesda, MD.
National Institutes of Health · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dried plant parts used as culinary spices (CSs) in food are permitted as dietary ingredients in dietary supplements (DSs) within certain constraints in the United States. We reviewed the amounts, forms, and nutritional support (structure/function) claims of DSs that contain CS plants listed in the Dietary Supplement Label Database (DSLD) and compared this label information with trial doses and health endpoints for CS plants that were the subject of clinical trials listed in clinicaltrials.gov. According to the DSLD, the CS plants occurring most frequently in DSs were cayenne, cinnamon, garlic, ginger, pepper, rosemary, and turmeric. Identifying the botanical species, categorizing the forms used, and determining the amounts from the information provided on DS labels was challenging. CS plants were typically added as a component of a blend, as the powered biomass, dried extracts, and isolated phytochemicals. The amounts added were declared on about 55% of the labels, rendering it difficult to determine the amount of the CS plant used in many DSs. Clinicaltrials.gov provided little information about the composition of test articles in the intervention studies. When plant names were listed on DS labels and in clinical trials, generally the common name and not the Latin binomial name was given. In order to arrive at exposure estimates and enable researchers to reproduce clinical trials, the Latin binomial name, form, and amount of the CS plant used in DSs and tested in clinical trials must be specified.

Indexed as

Food LabelingClinical Trials as TopicData AccuracyDatabases, FactualDietary SupplementsHumansInternetNational Institutes of Health (U.S.)Plant PreparationsPlants, EdibleServing SizeSpicesUnited StatesUnited States Food and Drug AdministrationVoluntary ProgramsPlant Preparationsbotanicalsclinicaltrials.govculinary spice plantsdietary ingredientsdietary supplementsDSLD

Identifiers

PMID26980817
PMCPMC4785482
OpenAlexW2299135596

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.