Evidence map›Paper›PMID 26980718›Full record

ArticleAmerican journal of Alzheimer's disease and other dementias2016

Hydrogen Proton Magnetic Resonance Spectroscopy in Multidomain Amnestic Mild Cognitive Impairment and Vascular Cognitive Impairment Without Dementia.

Shuang-Qing Chen, Qing Cai, Yu-Ying Shen, Chuan-Xiao Xu, Hua Zhou, Zhong Zhao

Open access · greenAbstract read
In one paragraph

Article in American journal of Alzheimer's disease and other dementias, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Shuang-Qing ChenDepartment of Radiology, The Affiliated Suzhou Hospital, Nanjing Medical University, Suzhou, China sznaonao@163.com.
Qing CaiDepartment of Radiology, The Affiliated Suzhou Hospital, Nanjing Medical University, Suzhou, China.
Yu-Ying ShenDepartment of Radiology, The Affiliated Suzhou Hospital, Nanjing Medical University, Suzhou, China.
Chuan-Xiao XuDepartment of Radiology, The Affiliated Suzhou Hospital, Nanjing Medical University, Suzhou, China.
Hua ZhouDepartment of Neurology, The Affiliated Suzhou Hospital, Nanjing Medical University, Suzhou, China.
Zhong ZhaoDepartment of Neurology, The Affiliated Suzhou Hospital, Nanjing Medical University, Suzhou, China.
Nanjing Medical University · CNSuzhou Municipal Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To investigate the value of hydrogen proton magnet resonance spectroscopy ((1)H-MRS) in the differential diagnosis of multiple-domain amnestic mild cognitive impairment (M-aMCI) and vascular cognitive impairment with no dementia (VCIND); (1)H-MRS was performed in patients with M-aMCI and VCIND. The level was determined for N-acetylaspartate (NAA), glutamate (Glu), inositol (mI), choline (Cho), and creatine (Cr). Compared with the normal control group, the NAA-Cr ratio in all regions studied was significantly lower in the M-aMCI and VCIND groups. The Glu-Cr ratio in the posterior cingulate gyrus of the M-aMCI group was significantly lower than in the VCIND. The mI-Cr ratio in the frontal white matter of the VCIND was significantly higher than in the M-aMCI group. In the white matter adjacent to the lateral ventricles, the Cho-Cr ratio was significantly higher in the VCIND than the M-aMCI. Our results suggested (1)H-MRS is an effective method in the differential diagnosis of M-aMCI and VCIND.

Indexed as

AgedAmnesiaCerebrovascular DisordersCognitive DysfunctionDiagnosis, DifferentialFemaleHumansMaleProton Magnetic Resonance SpectroscopyAlzheimer’s diseasemagnet resonance spectroscopymulti-domain amnestic mild cognitive impairmentvascular cognitive impairment without dementia

Identifiers

PMID26980718
PMCPMC10852783
OpenAlexW2299796069

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.