Evidence map›Paper›PMID 26980447›Full record

ReviewDocumenta ophthalmologica. Advances in ophthalmology2016

Treatment of vitamin A deficiency retinopathy with sublingual vitamin A palmitate.

James R Singer, Benjamin Bakall, Grant M Gordon, Rahul K Reddy

Abstract readCase ReportsReview
PubMed Publisher
In one paragraph

Review in Documenta ophthalmologica. Advances in ophthalmology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 23 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Functional food: complementary to fight against COVID-19.Beni-Suef University journal of basic and applied sciences · 2022
    Review
  8. Article
  9. Review
  10. Article
  11. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

James R SingerAssociated Retina Consultants, 1750 East Glendale Avenue, Phoenix, AZ, 85020, USA.
Benjamin BakallAssociated Retina Consultants, 1750 East Glendale Avenue, Phoenix, AZ, 85020, USA.
Grant M GordonAssociated Retina Consultants, 1750 East Glendale Avenue, Phoenix, AZ, 85020, USA.
Rahul K ReddyAssociated Retina Consultants, 1750 East Glendale Avenue, Phoenix, AZ, 85020, USA. rreddy375@yahoo.com.
University of Arizona · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo report treatment of vitamin A deficiency retinopathy with sublingual vitamin A drops.

methodsCase report with review of the literature.

resultsA 69-year-old Caucasian woman with a history of small bowel resection presented with progressive symptoms of bilateral nyctalopia and decreased visual acuity. Ophthalmic examination revealed bilateral conjunctival xerosis and fine white granular deposits in the midperipheral retina suggestive of vitamin A deficiency. Full-field electroretinogram (ERG), multifocal ERG (mfERG), and two-color dark adaptometry revealed significant impairment of rod and cone photoreceptor function. Kinetic perimetry demonstrated depressed macular sensitivity with constriction of the finer isopters. After 5 months of treatment with sublingual vitamin A drops, the patient's vision, ERG, mfERG, dark adaptometry, and perimetry normalized. A review of the literature summarizing the electrophysiologic testing in vitamin A deficiency is also discussed.

conclusionsThis case highlights novel observations on the effects of sublingual vitamin A supplementation for acquired vitamin A deficiency retinopathy. Sublingual vitamin A may represent a viable and efficacious treatment modality for vitamin A deficiency.

Indexed as

Administration, SublingualAgedDiterpenesElectroretinographyFemaleHumansNight BlindnessRetinaRetinyl EstersVisual AcuityVisual FieldsVisual Field TestsVitamin AVitamin A DeficiencyDiterpenesretinol palmitateRetinyl EstersVitamin ADark adaptometryERGmfERGVisual fieldsVitamin A deficiency

Identifiers

PMID26980447
OpenAlexW2301266262

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.