Evidence map›Paper›PMID 26980444›Full record

ArticleScientific reports2016

Optimizing matching and analysis combinations for estimating causal effects.

K Ellicott Colson, Kara E Rudolph, Scott C Zimmerman, Dana E Goin, Elizabeth A Stuart, Mark van der Laan, Jennifer Ahern

Abstract read
In one paragraph

Article in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

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  20. Performing an Informatics Consult: Methods and Challenges.Journal of the American College of Radiology : JACR · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

K Ellicott ColsonDivision of Epidemiology, University of California- Berkeley School of Public Health, 50 University Hall, Berkeley, CA 94720-7360, USA.
Kara E RudolphDivision of Epidemiology, University of California- Berkeley School of Public Health, 50 University Hall, Berkeley, CA 94720-7360, USA.
Scott C ZimmermanDivision of Epidemiology, University of California- Berkeley School of Public Health, 50 University Hall, Berkeley, CA 94720-7360, USA.
Dana E GoinDivision of Epidemiology, University of California- Berkeley School of Public Health, 50 University Hall, Berkeley, CA 94720-7360, USA.
Elizabeth A StuartDepartments of Mental Health, Biostatistics, and Health Policy and Management, Johns Hopkins Bloomberg School of Public Health, 624 N Broadway, Baltimore, MD 21205, USA.
Mark van der LaanDivision of Biostatistics, University of California- Berkeley School of Public Health, 101 Haviland Hall, Berkeley, CA 94720-7358, USA.
Jennifer AhernDivision of Epidemiology, University of California- Berkeley School of Public Health, 50 University Hall, Berkeley, CA 94720-7360, USA.

Funding

Targeted Learning using adaptive designs for HIV Epidemic control in East AfricaR01AI074345 · NIAID · UNIVERSITY OF CALIFORNIA BERKELEY · PI PETERSEN, MAYA LIV, VANDERLAAN, MARK J · 2007 to 2023
$6.6M
A Rigorous System to Determine the Health Impacts of Policies and ProgramsDP2HD080350 · NICHD · UNIVERSITY OF CALIFORNIA BERKELEY · PI AHERN, JENNIFER · 2013 to 2013
$2.4M
Using propensity scores for causal inference with covariate measurement errorR01MH099010 · NIMH · JOHNS HOPKINS UNIVERSITY · PI STUART, ELIZABETH A. · 2013 to 2016
$1.1M
NCCDPHP CDC HHS DP2 HD080350NIAID NIH HHS 5R01AI074345-07NIAID NIH HHS R01 AI074345NICHD NIH HHS DP2 HD080350NIMH NIH HHS R01 MH099010NIMH NIH HHS R01MH099010
6 · The paper itself

Abstract

Matching methods are common in studies across many disciplines. However, there is limited evidence on how to optimally combine matching with subsequent analysis approaches to minimize bias and maximize efficiency for the quantity of interest. We conducted simulations to compare the performance of a wide variety of matching methods and analysis approaches in terms of bias, variance, and mean squared error (MSE). We then compared these approaches in an applied example of an employment training program. The results indicate that combining full matching with double robust analysis performed best in both the simulations and the applied example, particularly when combined with machine learning estimation methods. To reduce bias, current guidelines advise researchers to select the technique with the best post-matching covariate balance, but this work finds that such an approach does not always minimize mean squared error (MSE). These findings have important implications for future research utilizing matching. To minimize MSE, investigators should consider additional diagnostics, and use of simulations tailored to the study of interest to identify the optimal matching and analysis combination.

Indexed as

BiasData Interpretation, StatisticalComputer SimulationEducationEmploymentHumansModels, StatisticalPropensity ScoreQuality Improvement

Identifiers

PMID26980444
PMCPMC4793248

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.