ArticleHeredity2016
Mammalian X homolog acts as sex chromosome in lacertid lizards.
Article in Heredity, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed.
- Using a Handful of Transcriptomes to Detect Sex-Linked Markers and Develop Molecular Sexing Assays in a Species with Homomorphic Sex Chromosomes.Genome biology and evolution · 2024Article
- Heteromorphic ZZ/ZW sex chromosomes sharing gene content with mammalian XX/XY are conserved in Madagascan chameleons of the genus Furcifer.Scientific reports · 2024Article
- Sex-Linked Loci on the W Chromosome in the Multi-Ocellated Racerunner (Animals : an open access journal from MDPI · 2023Article
- Review
- Sex chromosome evolution among amniotes: is the origin of sex chromosomes non-random?Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2021Article
- Review
- Amplified Fragments of an Autosome-Borne Gene Constitute a Significant Component of the W Sex Chromosome ofGenes · 2021Article
- Differences in Homomorphic Sex Chromosomes Are Associated with Population Divergence in Sex Determination inCells · 2021Article
- Review
- Do sex chromosomes of snakes, monitor lizards, and iguanian lizards result from multiple fission of an "ancestral amniote super-sex chromosome"?Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology · 2020Article
- Article
- Review
- Long-term monitoring reveals invariant clutch size and unequal reproductive costs between sexes in a subtropical lacertid lizard.Zoological letters · 2020Article
- How to identify sex chromosomes and their turnover.Molecular ecology · 2019Review
- Escaping the evolutionary trap? Sex chromosome turnover in basilisks and related lizards (Corytophanidae: Squamata).Biology letters · 2019Article
- Little evidence for switches to environmental sex determination and turnover of sex chromosomes in lacertid lizards.Scientific reports · 2019Article
- Identification of sex chromosomes inComparative cytogenetics · 2019Article
- Putative Independent Evolutionary Reversals from Genotypic to Temperature-Dependent Sex Determination are Associated with Accelerated Evolution of Sex-Determining Genes in Turtles.Journal of molecular evolution · 2018Article
- Stable Cretaceous sex chromosomes enable molecular sexing in softshell turtles (Testudines: Trionychidae).Scientific reports · 2017Article
- Sequential Turnovers of Sex Chromosomes in African Clawed Frogs (G3 (Bethesda, Md.) · 2016Article
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Among amniotes, squamate reptiles are especially variable in their mechanisms of sex determination; however, based largely on cytogenetic data, some lineages possess highly evolutionary stable sex chromosomes. The still very limited knowledge of the genetic content of squamate sex chromosomes precludes a reliable reconstruction of the evolutionary history of sex determination in this group and consequently in all amniotes. Female heterogamety with a degenerated W chromosome typifies the lizards of the family Lacertidae, the widely distributed Old World clade including several hundreds of species. From the liver transcriptome of the lacertid Takydromus sexlineatus female, we selected candidates for Z-specific genes as the loci lacking single-nucleotide polymorphisms. We validated the candidate genes through the comparison of the copy numbers in the female and male genomes of T. sexlineatus and another lacertid species, Lacerta agilis, by quantitative PCR that also proved to be a reliable technique for the molecular sexing of the studied species. We suggest that this novel approach is effective for the detection of Z-specific and X-specific genes in lineages with degenerated W, respectively Y chromosomes. The analyzed gene content of the Z chromosome revealed that lacertid sex chromosomes are not homologous with those of other reptiles including birds, but instead the genes have orthologs in the X-conserved region shared by viviparous mammals. It is possible that this part of the vertebrate genome was independently co-opted for the function of sex chromosomes in viviparous mammals and lacertids because of its content of genes involved in gonad differentiation.
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