Evidence map›Paper›PMID 26979999›Full record

Trial reportArthritis research & therapy2016

Perceived function and physical performance are associated with pain and fatigue in women with fibromyalgia.

Dana L Dailey, Laura A Frey Law, Carol G T Vance, Barbara A Rakel, Ericka N Merriwether, Leon Darghosian, Meenakshi Golchha, Katharine M Geasland, Rebecca Spitz, Leslie J Crofford and 1 more

Registry-linked trialOpen access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Arthritis research & therapy, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01888640 (Fibromyalgia Activity Study With Transcutaneous Electrical Nerve Stimulation), which is not on this map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
1.9field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01888640 nacompletednot on this map

Fibromyalgia Activity Study With Transcutaneous Electrical Nerve Stimulation

TypeinterventionalSponsorKathleen SlukaRan2013 to 2018Enrolled301ConditionsFibromyalgiaArmsTENS
3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 45 citations in OpenAlex.

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  2. Effects of Manual Therapy on Fatigue, Pain, and Psychological Aspects in Women with Fibromyalgia.International journal of environmental research and public health · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Dana L DaileyDepartment of Physical Therapy and Rehabilitation Science, Carver College of Medicine, University of Iowa, 1-252 MEB, 500 Newton Road, Iowa City, IA, 52242, USA. dana-dailey@uiowa.edu.ORCID http://orcid.org/0000-0002-1239-7530
Laura A Frey LawDepartment of Physical Therapy and Rehabilitation Science, Carver College of Medicine, University of Iowa, 1-252 MEB, 500 Newton Road, Iowa City, IA, 52242, USA.
Carol G T VanceDepartment of Physical Therapy and Rehabilitation Science, Carver College of Medicine, University of Iowa, 1-252 MEB, 500 Newton Road, Iowa City, IA, 52242, USA.
Barbara A RakelDepartment of Physical Therapy and Rehabilitation Science, Carver College of Medicine, University of Iowa, 1-252 MEB, 500 Newton Road, Iowa City, IA, 52242, USA.
Ericka N MerriwetherDepartment of Physical Therapy and Rehabilitation Science, Carver College of Medicine, University of Iowa, 1-252 MEB, 500 Newton Road, Iowa City, IA, 52242, USA.
Leon DarghosianDepartment of Medicine, Division of Rheumatology & Immunology, Vanderbilt University, 1161 21st Avenue South, Nashville, TN, 37232, USA.
Meenakshi GolchhaDepartment of Medicine, Division of Rheumatology & Immunology, Vanderbilt University, 1161 21st Avenue South, Nashville, TN, 37232, USA.
Katharine M GeaslandDepartment of Physical Therapy and Rehabilitation Science, Carver College of Medicine, University of Iowa, 1-252 MEB, 500 Newton Road, Iowa City, IA, 52242, USA.
Rebecca SpitzDepartment of Physical Therapy and Rehabilitation Science, Carver College of Medicine, University of Iowa, 1-252 MEB, 500 Newton Road, Iowa City, IA, 52242, USA.
Leslie J CroffordDepartment of Medicine, Division of Rheumatology & Immunology, Vanderbilt University, 1161 21st Avenue South, Nashville, TN, 37232, USA.
Kathleen A SlukaDepartment of Physical Therapy and Rehabilitation Science, Carver College of Medicine, University of Iowa, 1-252 MEB, 500 Newton Road, Iowa City, IA, 52242, USA.
University of Iowa · USVanderbilt University · US

Funding

The University of Iowa Clinical and Translational Science AwardU54TR001356 · NCATS · UNIVERSITY OF IOWA · PI WINOKUR, PATRICIA · 2015 to 2016
$7.1M
University of Iowa Institute for Clinical and Translational ScienceU54TR001013 · NCATS · UNIVERSITY OF IOWA · PI ROSENTHAL, GARY E · 2014 to 2014
$4.2M
NCATS NIH HHS 54TR001013NCATS NIH HHS U54 TR001013NCATS NIH HHS U54 TR001356NCATS NIH HHS U54TR001356NIAMS NIH HHS UM1 AR06338NIAMS NIH HHS UM1AR06338-S1
6 · The paper itself

Abstract

backgroundFibromyalgia is a condition characterized by chronic widespread muscle pain and fatigue and associated with significant impairment in perceived function and reduced physical performance. The purpose of this study was to determine the degree to which pain and fatigue are associated with perceived function and physical performance in women with fibromyalgia.

methodsHierarchical linear regression determined the contribution of pain and fatigue (Numeric Rating Scale (NRS) for resting, movement and combined) to perceived function (Fibromyalgia Impact Questionnaire Revised - Function Subscale, FIQR-Function), Multidimensional Assessment of Fatigue - Activities of Daily Living (MAF-ADL) and SF-36 Physical Function Subscale (SF-36-PF) and physical performance (6-Minute Walk Test, 6MWT and Five Time Sit To Stand, 5TSTS) while controlling for age, body mass index, pain catastrophizing, fear of movement, anxiety, and depression in women with fibromyalgia (N = 94).

resultsFor perceived function, movement pain and movement fatigue together better predicted FIQR-function (adjusted R(2) = 0.42, p ≤ 0.001); MAF-ADL (adjusted R(2) = 0.41, p ≤ 0.001); and SF-36-PF function (adjusted R(2) = 0.34, p ≤ 0.001). For physical performance measures, movement pain and fatigue together predicted 6MWT distance (adjusted R(2) = 0.42, p ≤ 0.001) and movement fatigue alone predicted performance time on the 5TSTS (adjusted R(2) = 0.20, p ≤ 0.001).

conclusionsPain and fatigue are significantly associated with and explain more than one-third of the variance in perceived function and physical performance in women with fibromyalgia.

trial registrationNIH Clinicaltrials.gov REGISTRATION: NCT01888640 . Registered 13 June 2013.

Indexed as

Activities of Daily LivingAdultAgedChronic PainFatigueFemaleFibromyalgiaHumansLinear ModelsMiddle AgedPerceptionSeverity of Illness IndexTranscutaneous Electric Nerve StimulationYoung Adult

Identifiers

PMID26979999
PMCPMC4793621
OpenAlexW2299784597

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.