ArticleEuropean journal of clinical nutrition2016
Vitamin D and incident urinary incontinence in older adults.
Article in European journal of clinical nutrition, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 34 citations in OpenAlex.
- Severe Vitamin D Deficiency-A Possible Cause of Resistance to Treatment in Psychiatric Pathology.Medicina (Kaunas, Lithuania) · 2023Pooled it
- The effect of vitamin D on urgent urinary incontinence in postmenopausal women.International urogynecology journal · 2023Trial
- Effect of Vitamin D Supplementation on Overactive Bladder and Urinary Incontinence Symptoms in Older Men: Ancillary Findings From a Randomized Trial.The Journal of urology · 2023Trial
- Effect of vitamin D supplementation on the severity of stress urinary incontinence in premenopausal women with vitamin D insufficiency: a randomized controlled clinical trial.BMC women's health · 2022Trial
- Effect of vitamin D supplementation on urinary incontinence in older women: ancillary findings from a randomized trial.American journal of obstetrics and gynecology · 2022Trial
- Comparing Vitamin D Supplementation Versus Placebo for Urgency Urinary Incontinence: A Pilot Study.Journal of the American Geriatrics Society · 2019Trial
- Association between serum 25-hydroxyvitamin D concentrations and overactive bladder in female: a mediation analysis of inflammatory biomarkers.Frontiers in nutrition · 2026Article
- Associations Between the Number of Vaginal Delivery and Urinary Incontinence in Women Before and After Natural Menopause: A Cross-Sectional Study.International journal of women's health · 2025Article
- U-shaped association between serum 25-hydroxyvitamin D concentrations and urinary leakage among adult females aged 45 years and over in the United States: a cross-sectional study.BMC women's health · 2024Article
- Total and free 25-hydroxyvitamin D concentrations and risk of urinary incontinence in women participating in Nurses Health Studies I & II.The American journal of the medical sciences · 2023Article
- Association of fat-soluble vitamins (A, D, and E) status with humoral immune response to COVID-19 inactivated vaccination.Frontiers in nutrition · 2023Article
- Association of vitamin D deficiency and pelvic organ prolapse in postmenopausal women: a cross-sectional study.Women's midlife health · 2022Article
- The effect of vitamin D deficiency and supplementation on urinary incontinence: scoping review.International urogynecology journal · 2022Article
- Clinical significance of vitamin D in idiopathic normal pressure hydrocephalus.Acta neurochirurgica · 2021Article
- Article
- Comparison of Serum Vitamin D Levels in Relation to Bowel and Bladder Symptoms in Women with Vulvar Diseases.International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition · 2020Article
- Vitamin D intake and the 10-year risk of urgency urinary incontinence in women.The Journal of steroid biochemistry and molecular biology · 2020Article
- The association between vitamin D and urinary incontinence.European journal of clinical nutrition · 2016Article
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Authors and funding
9 authors at 4 institutions in 1 country.
Funding
Abstract
BACKGROUND/
objectivesThe aim of this study is to determine whether vitamin D status is associated with incident urinary incontinence (UI) among community-dwelling older adults. SUBJECTS/
methodsThe University of Alabama at Birmingham Study of Aging is a prospective cohort study of community-dwelling Medicare enrollees. Standardized assessment of UI was conducted using the validated Incontinence Severity Index. The analysis of 25-hydroxyvitamin D [25(OH)D] levels was performed on stored baseline sera. UI was assessed every 6-12 months for up to 42 months. The analyses included multivariable logistic regression and Cox proportional hazard models.
resultsOf 350 participants (175 male, 147 black, mean age 73.6±5.8), 54% (189/350) were vitamin D deficient (25(OH)D <20 ng/ml) and 25% (87/350) were vitamin D insufficient (25(OH)D: 20 ng/ml to <30 ng/ml). Among the 187 subjects with no UI at baseline, 57% (107/187) were vitamin D deficient and 24% (45/187) were vitamin D insufficient. A total of 175 of the 187 subjects had follow-up evaluation for incident UI over 42 months, and incident UI occurred in 37% (65/175). After adjustment, cumulative incident UI at 42 months was associated with baseline vitamin D insufficiency (P=0.03) and demonstrated a trend association with deficiency (P=0.07). There was no association between baseline vitamin D status and the time to incident UI.
conclusionsThese preliminary results support an association between vitamin D and incident UI in community-dwelling older adults. Future studies may target specific at-risk groups, such as men with BPH or women with pelvic floor disorders for evaluation of the impact of vitamin D supplementation on urinary symptoms.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.