Evidence map›Paper›PMID 26979832›Full record

ArticleBMC pediatrics2016

The large contribution of twins to neonatal and post-neonatal mortality in The Gambia, a 5-year prospective study.

Reiko Miyahara, Momodou Jasseh, Grant Austin Mackenzie, Christian Bottomley, M Jahangir Hossain, Brian M Greenwood, Umberto D'Alessandro, Anna Roca

Open access · goldAbstract read
In one paragraph

Article in BMC pediatrics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
9.8field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 32 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 4 countries.

Reiko MiyaharaMedical Research Council, Banjul, The Gambia.
Momodou JassehMedical Research Council, Banjul, The Gambia.
Grant Austin MackenzieMedical Research Council, Banjul, The Gambia.
Christian BottomleyFaculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, UK.
M Jahangir HossainMedical Research Council, Banjul, The Gambia.
Brian M GreenwoodFaculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, UK.
Umberto D'AlessandroMedical Research Council, Banjul, The Gambia.
Anna RocaMedical Research Council, Banjul, The Gambia. aroca@mrc.gm.
London School of Hygiene & Tropical Medicine · GBMRC Unit the Gambia · GM

Funding

Medical Research Council MC_UP_A900_1119Medical Research Council MC_UP_A900_1123Medical Research Council MR/K012126/1
6 · The paper itself

Abstract

backgroundA high twinning rate and an increased risk of mortality among twins contribute to the high burden of infant mortality in Africa. This study examined the contribution of twins to neonatal and post-neonatal mortality in The Gambia, and evaluated factors that contribute to the excess mortality among twins.

methodsWe analysed data from the Basse Health and Demographic Surveillance System (BHDSS) collected from January 2009 to December 2013. Demographic and epidemiological variables were assessed for their association with mortality in different age groups.

resultsWe included 32,436 singletons and 1083 twins in the analysis (twining rate 16.7/1000 deliveries). Twins represented 11.8 % of all neonatal deaths and 7.8 % of post-neonatal deaths. Mortality among twins was higher than in singletons [adjusted odds ratio (AOR) 4.33 (95 % CI: 3.09, 6.06) in the neonatal period and 2.61 (95 % CI: 1.85, 3.68) in the post-neonatal period]. Post-neonatal mortality among twins increased in girls (P for interaction = 0.064), being born during the dry season (P for interaction = 0.030) and lacking access to clean water (P for interaction = 0.042).

conclusionMortality among twins makes a significant contribution to the high burden of neonatal and post-neonatal mortality in The Gambia and preventive interventions targeting twins should be prioritized.

Indexed as

Infant MortalityFemaleGambiaHumansInfantInfant, NewbornLogistic ModelsMaleOdds RatioProspective StudiesRisk FactorsTwinsHDSSMortalityNeonatalPost-neonatalRisk factorsTwins

Identifiers

PMID26979832
PMCPMC4791939
OpenAlexW2299505882

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.