Evidence map›Paper›PMID 26979387›Full record

ArticleJournal of psychopharmacology (Oxford, England)2016

Evidence-based guidelines for treating bipolar disorder: Revised third edition recommendations from the British Association for Psychopharmacology.

G M Goodwin, P M Haddad, I N Ferrier, J K Aronson, Trh Barnes, A Cipriani, D R Coghill, S Fazel, J R Geddes, H Grunze and 17 more

2 registry-linked trialsOpen access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of psychopharmacology (Oxford, England), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 281 papers, 22 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
281citing papers in PubMed, 22 pooled it
81.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04797351 nacompletednot on this mapstarted 2020, after this paper: background citation

Acceptability and Feasibility of a DBT Skills Group Intervention for Bipolar Disorder - a Randomized Pilot Trial

TypeinterventionalSponsorJulieta AzevedoRan2020 to 2022Enrolled109ConditionsBipolar DisorderArmsDialectical Behavior Therapy - Skills
NCT05157386 active not recruitingnot on this mapstarted 2021, after this paper: background citation

Physical Exercise as Adjunctive Therapy for Affective Disorder and Anxiety - a Retrospective Study of the Braining Project 2017-2020 Regarding Feasibility, Participants and Changes in Symptoms, Function and Physical Parameters

TypeobservationalSponsorRegion StockholmRan2021 to 2025Enrolled50ConditionsDepression, Physical Inactivity, Bipolar Disorder, Anxiety DisordersArmsBraining
3 · Its place in the literature

Who cites it

281 citing papers in PubMed, 22 syntheses or guidelines pooled it, 1,281 citations in OpenAlex.

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  13. Lithium treatment of Bipolar disorder in adults: A systematic review of randomized trials and meta-analyses.European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology · 2022
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  20. Pharmacological Augmentation in Unipolar Depression: A Guide to the Guidelines.The international journal of neuropsychopharmacology · 2020
    Pooled it

221 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

27 authors at 20 institutions in 4 countries.

G M GoodwinUniversity Department of Psychiatry, Warneford Hospital, Oxford, UK guy.goodwin@psych.ox.ac.uk.
P M HaddadGreater Manchester West Mental Health NHS Foundation Trust, Eccles, Manchester, UK.
I N FerrierInstitute of Neuroscience, Newcastle University, UK and Northumberland Tyne and Wear NHS Foundation Trust, Newcastle, UK.
J K AronsonCentre for Evidence Based Medicine, Nuffield Department of Primary Care Health Sciences, Radcliffe Observatory Quarter, Oxford, UK.
Trh BarnesThe Centre for Mental Health, Imperial College London, Du Cane Road, London, UK.
A CiprianiUniversity Department of Psychiatry, Warneford Hospital, Oxford, UK.
D R CoghillMACHS 2, Ninewells' Hospital and Medical School, Dundee, UK; now Departments of Paediatrics and Psychiatry, Faculty of Medicine, Dentistry and Health Science, University of Melbourne, Melbourne, VIC, Australia.
S FazelUniversity Department of Psychiatry, Warneford Hospital, Oxford, UK.
J R GeddesUniversity Department of Psychiatry, Warneford Hospital, Oxford, UK.
H GrunzeUniv. Klinik f. Psychiatrie u. Psychotherapie, Christian Doppler Klinik, Universitätsklinik der Paracelsus Medizinischen Privatuniversität (PMU), Salzburg, Christian Doppler Klinik Salzburg, Austria.
E A HolmesMRC Cognition & Brain Sciences Unit, Cambridge, UK.
O HowesInstitute of Psychiatry (Box 67), London, UK.
S HudsonBipolar UK, London, UK.
N HuntFulbourn Hospital, Cambridge, UK.
I JonesMRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff, UK.
I C MacmillanNorthumberland, Tyne and Wear NHS Foundation Trust, Queen Elizabeth Hospital, Gateshead, Tyne and Wear, UK.
H McAllister-WilliamsInstitute of Neuroscience, Newcastle University, UK and Northumberland Tyne and Wear NHS Foundation Trust, Newcastle, UK.
D R MiklowitzUCLA Semel Institute for Neuroscience and Human Behavior, Division of Child and Adolescent Psychiatry, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA.
R MorrissDivision of Psychiatry and Applied Psychology, Institute of Mental Health, University of Nottingham Innovation Park, Nottingham, UK.
M MunafòMRC Integrative Epidemiology Unit, UK Centre for Tobacco and Alcohol Studies, School of Experimental Psychology, University of Bristol, Bristol, UK.
C PatonOxleas NHS Foundation Trust, Dartford, UK.
B J SaharkianDepartment of Psychiatry (Box 189), University of Cambridge School of Clinical Medicine, Addenbrooke's Hospital, Cambridge, UK.
Kea SaundersUniversity Department of Psychiatry, Warneford Hospital, Oxford, UK.
Jma SinclairUniversity Department of Psychiatry, Southampton, UK.
D TaylorSouth London and Maudsley NHS Foundation Trust, Pharmacy Department, Maudsley Hospital, London, UK.
E VietaHospital Clinic, University of Barcelona, IDIBAPS, CIBERSAM, Barcelona, Spain.
A H YoungCentre for Affective Disorders, King's College London, London, UK.
Warneford Hospital · GBNewcastle University · GBAddenbrooke's Hospital · GBCardiff University · GBCentre for Mental Health · GBChristian Doppler Klinik · ATConsorci Institut D'Investigacions Biomediques August Pi I Sunyer · ESFulbourn Hospital · GBGreater Manchester Mental Health NHS Foundation Trust · GBKing's College London · GBMaudsley Hospital · GBMRC Cognition and Brain Sciences Unit · GBNuffield Health · GBOxleas NHS Foundation Trust · GBPsychiatry Research Trust · GBQueen Elizabeth Hospital · GBUK Centre for Tobacco & Alcohol Studies · GBUniversity of Melbourne · AUUniversity of Nottingham · GBUniversity of Southampton · GB

Funding

Medical Research Council G0700995Medical Research Council MC_U120097115Medical Research Council MC_UP_0901/1Medical Research Council MR/L010305/1Wellcome Trust 095806
6 · The paper itself

Abstract

The British Association for Psychopharmacology guidelines specify the scope and targets of treatment for bipolar disorder. The third version is based explicitly on the available evidence and presented, like previous Clinical Practice Guidelines, as recommendations to aid clinical decision making for practitioners: it may also serve as a source of information for patients and carers, and assist audit. The recommendations are presented together with a more detailed review of the corresponding evidence. A consensus meeting, involving experts in bipolar disorder and its treatment, reviewed key areas and considered the strength of evidence and clinical implications. The guidelines were drawn up after extensive feedback from these participants. The best evidence from randomized controlled trials and, where available, observational studies employing quasi-experimental designs was used to evaluate treatment options. The strength of recommendations has been described using the GRADE approach. The guidelines cover the diagnosis of bipolar disorder, clinical management, and strategies for the use of medicines in short-term treatment of episodes, relapse prevention and stopping treatment. The use of medication is integrated with a coherent approach to psychoeducation and behaviour change.

Indexed as

Evidence-Based MedicinePractice Guidelines as TopicAntidepressive AgentsBipolar DisorderCombined Modality TherapyConsensusDiagnosis, DifferentialHumansMedication AdherencePatient Education as TopicPsychopharmacologySecondary PreventionAntidepressive AgentsantidepressantsantipsychoticsBipolar disordercognitive behaviour therapyevidence-based guidelineslithiummood stabilizerspsychoeducationtreatment

Identifiers

PMID26979387
PMCPMC4922419
OpenAlexW2003490971

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.