Evidence map›Paper›PMID 26979058›Full record

ArticleBMC pregnancy and childbirth2016

Awareness of cytomegalovirus and risk factors for susceptibility among pregnant women, in Montreal, Canada.

Sarah Wizman, Valérie Lamarre, Lena Coic, Fatima Kakkar, Jean-Baptiste Le Meur, Céline Rousseau, Marc Boucher, Bruce Tapiero

Open access · goldAbstract read
In one paragraph

Article in BMC pregnancy and childbirth, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it, 52 citations in OpenAlex.

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  14. Using blood donors and solid organ transplant donors and recipients to estimate the seroprevalence of cytomegalovirus and Epstein-Barr virus in Canada: A cross-sectional study.Journal of the Association of Medical Microbiology and Infectious Disease Canada = Journal officiel de l'Association pour la microbiologie medicale et l'infectiologie Canada · 2020
    Article
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  17. [A review on the prevention and treatment of congenital cytomegalovirus infection in mothers and infants].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2018
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  20. Prevalence and Social Risk Factors for Hearing Impairment in Chinese Children-A National Survey.International journal of environmental research and public health · 2017
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Sarah WizmanInfectious Disease Division, Department of Paediatrics, CHU Sainte Justine, Université de Montréal, 3175 Ch. de la Cote-Sainte-Catherine (bureau 7412), Montréal, H3T1C5, , QC, Canada. lydasa@yahoo.com.ORCID http://orcid.org/0000-0001-6144-6952
Valérie LamarreInfectious Disease Division, Department of Paediatrics, CHU Sainte Justine, Université de Montréal, 3175 Ch. de la Cote-Sainte-Catherine (bureau 7412), Montréal, H3T1C5, , QC, Canada.
Lena CoicInfectious Disease Division, Department of Paediatrics, CHU Sainte Justine, Université de Montréal, 3175 Ch. de la Cote-Sainte-Catherine (bureau 7412), Montréal, H3T1C5, , QC, Canada.
Fatima KakkarInfectious Disease Division, Department of Paediatrics, CHU Sainte Justine, Université de Montréal, 3175 Ch. de la Cote-Sainte-Catherine (bureau 7412), Montréal, H3T1C5, , QC, Canada.
Jean-Baptiste Le MeurDepartment of Social and Preventive Medicine, Faculty of Medicine, Laval University, Pavillon Ferdinand-Vandry (bureau 4633), 1050 Av de la Medicine, Québec, G1V0A6, QC, Canada.
Céline RousseauInfectious Disease Division, Department of Paediatrics, CHU Sainte Justine, Université de Montréal, 3175 Ch. de la Cote-Sainte-Catherine (bureau 7412), Montréal, H3T1C5, , QC, Canada.
Marc BoucherObstetric and Gynecology Department, CHU Sainte Justine, Université de Montréal, 3175 Ch. de la Cote-Sainte-Catherine (bureau 4822), Montréal, H3T1C5, , QC, Canada.
Bruce TapieroInfectious Disease Division, Department of Paediatrics, CHU Sainte Justine, Université de Montréal, 3175 Ch. de la Cote-Sainte-Catherine (bureau 7412), Montréal, H3T1C5, , QC, Canada.
Centre Hospitalier Universitaire Sainte-Justine · CAUniversité Laval · CAYahoo (United Kingdom) · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAdvances in diagnostic and therapeutic modalities for congenital cytomegalovirus (CMV) infection have generated a mounting interest in identifying mothers susceptible to CMV. The objectives of this study were to evaluate the prevalence and socio-demographic determinants of CMV susceptibility and CMV awareness, among pregnant women, in Montreal, Quebec.

methodsBetween April and December 2012, women delivering at Centre Hospitalier Universitaire Sainte Justine were recruited for the study. Stored serum from the first trimester of pregnancy was tested for CMV IgG. Knowledge about CMV and socio-demographic characteristics were collected via standardized questionnaire.

resultsFour hundred and ninety one women were enrolled in the study. Overall, 225 mothers (46%) were seronegative for CMV, and 85% (n = 415) were unaware of CMV or the associated risks in pregnancy. Significant risk factors for CMV seronegative status included Canadian vs. foreign born (aOR 6.88, 95% CI 4.33-10.94), and high vs. low family income (aOR 4.68, 95% CI 2.09-10.48). Maternal employment status was the only significant predictor of CMV unawareness, with unemployed mothers at the highest risk (aOR 85.6, 95% CI 17.3-421.3).

conclusionsNearly half of pregnant women studied were at risk of primary infection, and yet, the majority was unaware of potential risks associated with CMV. Canadian born mothers and those with a high socioeconomic status were more likely to be CMV seronegative. Increased education about CMV infection, through public health interventions and obstetrician/pediatric counseling, is needed for all pregnant women.

Indexed as

CytomegalovirusHealth Knowledge, Attitudes, PracticeAdolescentAdultCytomegalovirus InfectionsFemaleHumansImmunoglobulin GPregnancyPregnancy Complications, InfectiousPregnancy Trimester, FirstPregnant PeopleQuebecRisk FactorsSeroepidemiologic StudiesYoung AdultImmunoglobulin GAwarenessCytomegalovirusPregnant womenSerostatusSocio-demographic risk factors

Identifiers

PMID26979058
PMCPMC4793542
OpenAlexW2297434793

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.