Evidence map›Paper›PMID 26977746›Full record

Trial reportJournal of acquired immune deficiency syndromes (1999)2016

Nucleoside-Sparing Regimens With Raltegravir and a Boosted Protease Inhibitor: An Unsettled Issue.

Maile Y Karris, Sonia Jain, Vi Q Bowman, Gunter Rieg, Miguel Goicoechea, Michael P Dube, Shubha Kerkar, Carol Kemper, Catherine Diamond, Xiaoying Sun and 4 more

Abstract readLetterMulticenter StudyRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Journal of acquired immune deficiency syndromes (1999), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Trial
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Maile Y Karris*Department of Medicine, University of California, San Diego, CA †Department of Family Medicine and Public Health, University of California, San Diego, CA ‡Kaiser Permanente, San Diego, CA §Scripps Health San Diego, San Diego, CA ‖Department of Medicine, University of Southern California Keck School of Medicine, Los Angeles, CA ¶Desert Regional Medical Center, Palm Springs, CA #Santa Clara Valley Medical Center, San Jose, CA **University California Irvine, Irvine, CA ††Los Angeles Biomedical Research Institute, Harbor-UCLA Medical Center and the David Geffen School of Medicine at UCLA, Los Angeles, CA ‡‡Gilead Sciences, Foster City, CA.
Sonia Jain
Vi Q Bowman
Gunter Rieg
Miguel Goicoechea
Michael P Dube
Shubha Kerkar
Carol Kemper
Catherine Diamond
Xiaoying Sun
Eric S Daar
Richard H Haubrich
Sheldon Morris
California Collaborative Treatment Group (CCTG) 589 Study Team

Funding

VirologyP30AI036214 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Maile Ann Young Karris · 1994 to 2026
$78.4M
Primary Infection Resource Consortium (PIRC)R24AI106039 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI LITTLE, SUSAN JANET · 2013 to 2021
$23.1M
Efficacy of ART to Interrupt HIV Transmission NetworksR01MH100974 · NIMH · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI LITTLE, SUSAN JANET · 2014 to 2018
$3.2M
Screening for atherosclerotic vascular disease in HIV-infected childrenR01HD083042 · NICHD · STELLENBOSCH UNIVERSITY · PI HAUBRICH, RICHARD H, INNES, STEVE · 2015 to 2019
$1.6M
NIAID NIH HHS P30 AI036214NIAID NIH HHS R24 AI106039NICHD NIH HHS R01 HD083042NIMH NIH HHS R01 MH100974
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AdultAlkynesAnti-HIV AgentsAtazanavir SulfateBenzoxazinesCyclopropanesDose-Response Relationship, DrugDrug Therapy, CombinationEmtricitabineFemaleHIV InfectionsHIV Protease InhibitorsHumansLopinavirMaleMiddle AgedAlkynesAnti-HIV AgentsAtazanavir SulfateBenzoxazinesCyclopropanesefavirenzEmtricitabineHIV Protease InhibitorsLopinavirRaltegravir PotassiumRitonavirRNA, ViralTenofovir

Identifiers

PMID26977746
PMCPMC4867124

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.