ArticleCurrent opinion in behavioral sciences2016
Self-medication with sucrose.
Article in Current opinion in behavioral sciences, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 41 citations in OpenAlex.
- Trial
- Glucose as fuel for HPA axis regulation: A narrative review on energy metabolism, stress reactivity, and early life adversity.Comprehensive psychoneuroendocrinology · 2026Review
- Examining the non-linear relationship between sugar consumption and anxiety symptoms in UK biobank data.Nutrition journal · 2026Article
- Effects of Perceived Stress on Problematic Eating: Three Parallel Moderated Mediation Models.Nutrients · 2025Article
- Assessing the Influence of Low Doses of Sucrose on Memory Deficits in Fish Exposed to Common Insecticide Based on Fipronil and Pyriproxyfen.Current issues in molecular biology · 2024Article
- A neuronal coping mechanism linking stress-induced anxiety to motivation for reward.Science advances · 2023Article
- Stress to inflammation and anhedonia: Mechanistic insights from preclinical and clinical models.Neuroscience and biobehavioral reviews · 2023Review
- Article
- Real-World Intake of Dietary Sugars Is Associated with Reduced Cortisol Reactivity Following an Acute Physiological Stressor.Nutrients · 2023Article
- Sugar Beverage Habitation Relieves Chronic Stress-Induced Anxiety-like Behavior but Elicits Compulsive Eating Phenotype via vLSInternational journal of molecular sciences · 2022Article
- The Influence of Unlimited Sucrose Intake on Body Weight and Behavior-Findings from a Mouse Model.Brain sciences · 2022Article
- Anxiety and Depression: What Do We Know of Neuropeptides?Behavioral sciences (Basel, Switzerland) · 2022Review
- Intermittent social stress produces different short- and long-term effects on effort-based reward-seeking behavior.Behavioural brain research · 2022Article
- Corticotropin-releasing factor system in the lateral septum: Implications in the pathophysiology of obesity.Frontiers in molecular neuroscience · 2022Review
- A Possible Anti-anxiety Effect of Appetitive Aggression and a Possible Link to the Work of Donald Winnicott.Scandinavian journal of child and adolescent psychiatry and psychology · 2022Article
- Maternal mindful eating as a target for improving metabolic outcomes in pregnant women with obesity.Frontiers in bioscience (Landmark edition) · 2021Observational
- A Comparison of Sugar Intake between Individuals with High and Low Trait Anxiety: Results from the NutriNet-Santé Study.Nutrients · 2021Article
- History of child maltreatment and excessive dietary and screen time behaviors in young adults: Results from a nationally representative study.Preventive medicine · 2020Article
- Psychosocial Functioning, BMI, and Nutritional Behaviors in Women at Cardiovascular Risk.Frontiers in psychology · 2020Article
- Stress as a context: Stress causes relapse of inhibited food seeking if it has been associated with prior food seeking.Appetite · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
Abstract
For many individuals, stress promotes the consumption of sweet, high-sugar foods relative to healthier alternatives. Daily life stressors stimulate the overeating of highly-palatable foods through multiple mechanisms, including altered glucocorticoid, relaxin-3, ghrelin and serotonin signaling in brain. In turn, a history of consuming high-sugar foods attenuates the psychological (anxiety and depressed mood) and physiological (HPA axis) effects of stress. Together the metabolic and hedonic properties of sucrose contribute to its stress relief, possibly via actions in both the periphery (e.g., glucocorticoid receptor signaling in adipose tissue) and in the brain (e.g., plasticity in brain reward regions). Emerging work continues to reveal the bidirectional mechanisms that underlie the use of high-sugar foods as 'self-medication' for stress relief.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.